背景:宫颈癌是女性中最常见的人乳头瘤病毒(HPV)相关疾病。自2008年以来,在乌干达,人们通常建议对青春期前和青春期女孩进行HPV疫苗接种,作为宫颈癌的主要预防措施。然而,在乌干达,尤其是在里拉区,关于9~14岁女孩HPV疫苗接种和相关因素的文献有限.这项研究评估了里拉市9-14岁的在校女孩中HPV疫苗的摄取和相关因素,乌干达北部
方法:对里拉市245名9-14岁的小学女生进行了横断面研究,乌干达北部使用多阶段抽样技术对符合条件的参与者进行抽样,并使用面试官管理的问卷收集数据。使用SPSS23.0版分析数据。使用描述性统计和95%显著性水平的多变量逻辑回归分别鉴定HPV疫苗摄取水平和预测因子。
结果:在里拉市9-14岁的女学生中,HPV疫苗的接种量为19.6%(95%CI,14.8-25.1),乌干达北部女孩的平均年龄为12.11(±1.651)岁。与HPV疫苗摄取独立相关的预测因素包括;卫生工作者的建议[aOR9.09,95%CI(3.19-25.88),P≤0.001],在学校教授宫颈癌[,12.56,95%CI(4.60-34.28),P≤0.001],和接触外展诊所[,4.41,95%CI(1.37-14.19),P=0.013]。
结论:研究发现,里拉市五分之一的女生,乌干达北部接种HPV疫苗。在学校接受过子宫颈癌教育的女孩,接触外展诊所和接受卫生工作者推荐的患者接受HPV疫苗的几率高于其治疗部件.卫生部应加强以学校为基础的宫颈癌教育,提高人们对HPV疫苗接种的认识,并建议卫生工作者提高乌干达女学生的HPV疫苗使用率。
Cervical cancer is the most common Human Papilloma Virus (HPV)-related disease among women. Since 2008, HPV vaccination has been routinely recommended for pre-adolescent and adolescent girls in Uganda as the primary preventive measure for cervical cancer. However, in Uganda, most especially in Lira district, there is limited literature on HPV vaccination uptake and associated factors among girls aged 9-14years. This
study assessed the uptake of HPV vaccine and associated factors among in-school girls aged 9-14 years in Lira City, northern Uganda.
A cross-sectional
study was conducted among 245 primary school girls aged 9-14 years in Lira City, northern Uganda. Multistage sampling technique was used to sample eligible participants and data was collected using interviewer administered questionnaire. Data was analysed using SPSS version 23.0. Descriptive statistics and multivariate logistic regression at 95% level of significance were used to identify the level of HPV vaccine uptake and predictors respectively.
HPV vaccination uptake was at 19.6% (95% CI,14.8-25.1) among the school girls aged 9-14 years in Lira City, northern Uganda. The mean age of the girls was 12.11 (± 1.651) years. Predictors that were independently associated with HPV vaccine uptake included; recommendation from health worker [aOR 9.09, 95% CI (3.19-25.88), P ≤ 0.001], taught about cervical cancer at school [aOR,12.56, 95% CI (4.60-34.28), P ≤ 0.001], and exposure to outreach clinics [aOR, 4.41, 95% CI (1.37-14.19), P = 0.013].
The
study found that one in five of the school girls in Lira City, northern Uganda. received HPV vaccine. Girls who were taught about cervical cancer at school, exposure to outreach clinics and received health worker recommendation had more odds of receiving HPV vaccine than their counter parts. The Ministry of Health should strengthen school based cervical cancer education, awareness raising about HPV vaccination and health worker recommendations to improve HPV vaccine uptake among school girls in Uganda.