与未怀孕育龄妇女的感染相比,怀孕期间的严重急性呼吸道综合症冠状病毒2(SARS-CoV-2)感染与严重发病率和死亡率的风险更高。越来越多的国家建议对孕妇进行SARS-CoV-2免疫接种。最近的研究提供了安全性的初步和支持性证据,2019冠状病毒病(COVID-19)疫苗在孕妇中的免疫原性和有效性;然而,重要的知识差距仍然存在,需要进一步研究。这篇合作的共识论文回顾了目前关于孕妇使用COVID-19疫苗的文献,确定知识差距,并概述未来研究的重点,以优化孕妇及其婴儿对SARS-CoV-2的保护。
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnancy is associated with a higher risk for severe morbidity and mortality when compared with infection in non-pregnant women of childbearing age. An increasing number of countries recommend immunization against SARS-CoV-2 in pregnant women. Recent studies provide preliminary and supportive evidence on safety, immunogenicity and effectiveness of coronavirus disease 2019 (COVID-19) vaccines in pregnant women; however, important knowledge gaps remain which warrant further studies. This collaborative
consensus paper provides a review of the current literature on COVID-19 vaccines in pregnant women, identifies knowledge gaps and outlines priorities for future research to optimize protection against SARS-CoV-2 in the pregnant women and their infants.