Acute myocardial infarction

急性心肌梗死
  • 文章类型: Case Reports
    背景:由于生活方式的改变,急性心肌梗死(AMI)的患病率正在增加,急性冠脉综合征(ACS)中不典型症状的发生率正在上升,这使得误诊这一致命事件的可能性增加.为了更好地处理症状不典型的患者,我们倾向于提出一个罕见的病例AMI与腕部疼痛。
    方法:一名41岁男子因严重的双手腕部疼痛和轻度上腹痛被送往急诊室(ER)。他的心电图(ECG)显示前ST抬高型心肌梗死(MI),射血分数为35-40%。他的血管造影显示左前降支严重,和第一钝缘动脉(OM1)动脉狭窄。他接受了直接经皮冠状动脉介入治疗(PCI)。患者康复,无严重并发症,PCI术后第二天出院。
    结论:在这种罕见的AMI伴腕部疼痛的病例中,重要的是要知道非典型症状可以存在于不同程度的症状中,防止将来误诊.
    BACKGROUND: As acute myocardial infarction (AMI) prevalence is increasing because of lifestyle changes, the incidence of atypical symptoms in acute coronary syndrome (ACS) is rising and making misdiagnosing of this fatal event more probable. To better approach the patients with atypical symptoms, we tend to present a rare case of AMI with wrist pain.
    METHODS: A 41-year-old man presented to the emergency room (ER) with severe both-hand wrist pain and mild epigastric pain. His electrocardiogram (ECG) showed anterior ST-elevation myocardial infarction (MI) with an ejection fraction of 35-40%. His angiography showed severe left anterior descending artery (LAD), and first obtuse marginal artery (OM1) artery stenosis. He underwent Primary percutaneous coronary intervention (PCI). The patient recovered without serious complications and was discharged the day after PCI.
    CONCLUSIONS: In this rare case of AMI with wrist pain, it is important to know that atypical symptoms can be present at various levels of symptoms, which prevents future misdiagnosis.
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  • 文章类型: Journal Article
    蛛网膜下腔出血(SAH)是一种罕见但随之而来的医疗紧急情况,可能模仿急性心肌梗塞(MI)。SAH导致交感神经活动增强,最终导致神经源性休克心肌(NSM)的发育,表示为ST段偏差,QT间期延长,T波反转或Q波。再灌注治疗是SAH的禁忌,因为出血和死亡的风险增加。因此,及时诊断至关重要。这里,我们报告了一例表现为弥漫性ST段偏离的大量SAH,模拟急性MI的独特病例。我们的患者在心脏骤停后被带到急诊室,并在入院第2天死亡。
    结论:蛛网膜下腔出血(SAH)可表现为心电图改变和肌钙蛋白显著升高,模仿急性冠脉综合征。SAH应包括在出现神经系统症状的患者的鉴别诊断中。ST段偏差或QT间期延长。将SAH误诊为急性冠状动脉综合征可导致抗凝剂的不当使用或延迟必要的神经系统干预措施。
    Subarachnoid haemorrhage (SAH) is a rare yet consequential medical emergency that may mimic an acute myocardial infarction (MI). SAH causes enhanced sympathetic activity, culminating in the development of neurogenic stunned myocardium (NSM), which presents as ST-segment deviations, prolonged QT intervals, T-wave inversions or Q-waves. Reperfusion therapy is contraindicated for SAH because of an increased risk of bleeding and death. Therefore, a prompt diagnosis is crucial. Here, we report a unique case of massive SAH presenting as diffuse ST-segment deviation simulating an acute MI. Our patient was brought to the emergency department after a cardiac arrest and died on day 2 of admission.
    CONCLUSIONS: Subarachnoid haemorrhage (SAH) can present with EKG changes and significant rise in troponin, mimicking acute coronary syndrome.SAH should be included in the differential diagnosis for patients presenting with neurological symptoms, ST-segment deviations or prolonged QT intervals.Misdiagnosis of SAH as acute coronary syndrome can lead to inappropriate use of anticoagulants or delays in necessary neurological interventions.
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  • 文章类型: Case Reports
    背景:由于介入治疗的时间,区分急性心肌梗死和Wellens综合征是重要且具有挑战性的。区分亚型的困难可能意味着患者被过度治疗或接受治疗不足。病例报告:一名57岁的男子因急性胸痛被转诊到我们的急诊病房。心电图(ECG)改变提示Wellens综合征A型。服用硝酸甘油,病人的胸痛消失了,我们计划了一个早期侵入性策略。在进行导管插入术之前,他先前有记录的ECG,并且根据第二次ECG变化提示ST抬高。作为侵入性策略的结果,发现有单支血管疾病,左前降支(LAD)与右冠状动脉侧支的中部几乎完全闭塞。在心血管重症监护病房(ICCU)观察两天后,患者病情好转,并转入低监护病房.结论:该病例突出了急性侧支动脉完全闭塞的Wellens综合征。
    UNASSIGNED: It is important and challenging to distinguish between acute myocardial infarction and Wellens syndrome due to its time to intervention. Difficulties in differentiating between subtypes could mean the patients are overtreated or receive undertreatment.
    UNASSIGNED: A 57-year-old man was referred to our emergency ward with acute onset of chest pain. Electrocardiograms changes were suggestive of type A Wellens syndrome. Nitroglycerin was administrated, the patient\'s chest pain disappeared, and we planned an early invasive strategy. He had a previous documented electrocardiogram before he went for catheterization and based on the second electrocardiogram changes were suggestive of an ST-elevation. As the result of the invasive strategy, it was found that there was single-vessel disease, critical occlusion in the middle of the left anterior descending artery coronary artery with collateral from the right coronary artery. After two days of observation in the Intensive Cardiovascular Care Unit, the patient improved and was transferred to Low Care Unit.
    UNASSIGNED: The case highlights Wellens syndrome in acute critical occlusion with collateral artery.
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  • 文章类型: Case Reports
    最近,中年人猝死的发生率令人担忧。主要是,心血管疾病成为这种不合时宜的死亡背后的主要原因。在这些悲剧性事件中,心肌梗塞及其随后的并发症是最常见的情况。尽管这是一个相对罕见的事件,心脏填塞是心肌梗死后可能发生的罕见但致命的并发症之一。这种情况表现在心包腔充满血液或血凝块时,妨碍心脏的正常功能.通常,据报道,患有心脏压塞的患者通常死于猝死,先前的胸痛病史是一个常见的指标。心脏压塞的明确诊断通常发生在尸检期间。我们考虑一名38岁的男子在其住所被发现失去知觉,并在到达医院时被宣布死亡。随后的尸检结果揭示了心包腔内存在血液和血凝块,伴随右心室破裂和左冠状动脉闭塞。组织病理学分析进一步证实了这一悲剧性事件的根本原因是急性心肌梗死。
    In recent times, there has been a concerning rise in the incidence of sudden death among individuals in middle age. Predominantly, cardiovascular diseases emerge as the leading cause behind such untimely fatalities. Myocardial infarction and its subsequent complications stand out as the most frequently encountered scenarios in these tragic events. Despite being a relatively uncommon occurrence, cardiac tamponade represents one of the rare yet fatal complications that can ensue following a myocardial infarction. This condition manifests when the pericardial cavity becomes filled with either blood or blood clots, impeding the heart\'s normal functioning. Typically, patients experiencing cardiac tamponade are often reported to have succumbed to sudden death, with a preceding history of chest pain being a common indicator. The definitive diagnosis of cardiac tamponade usually occurs during post-mortem examinations. We consider the case of a 38-year-old man who was discovered unconscious at his residence and was pronounced dead upon arrival at the hospital. Subsequent autopsy findings unveiled the presence of both blood and blood clots within the pericardial cavity, in conjunction with a rupture in the right ventricle and occlusion of the left coronary artery. Histopathological analysis further confirmed the root cause of this tragic event as an acute myocardial infarction.
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  • 文章类型: Case Reports
    主动脉缩窄是高血压和动脉粥样硬化疾病发展的主要危险因素。缺乏关于未经治疗的主动脉缩窄患者的急性冠状动脉综合征治疗的证据。
    50岁男性,有高血压病史,糖尿病,和血液动力学显著未经治疗的主动脉缩窄出现在急诊科的非ST段抬高急性心肌梗死。冠状动脉导管检查显示严重的三支血管疾病。使用覆膜CP支架经皮治疗主动脉缩窄。第二天进行了四次冠状动脉搭桥手术。手术后10天,他出院回家。
    我们描述了一种成功的序贯方法,包括在急性冠状动脉综合征的情况下,经皮修复天然主动脉缩窄,然后进行手术心肌血运重建。多学科心脏团队中的讨论对于具有这种复杂性的患者至关重要。
    UNASSIGNED: Aortic coarctation is a major risk factor for high blood pressure and atherosclerotic disease development. Evidence is lacking regarding the treatment of acute coronary syndrome in patients with untreated aortic coarctation.
    UNASSIGNED: A 50-year-old male with a history of hypertension, diabetes, and haemodynamically significant untreated aortic coarctation presented to the emergency department with non-ST-elevation acute myocardial infarction. Coronary catheterization showed severe three-vessel disease. The aortic coarctation was addressed percutaneously using a covered CP stent. A quadruple coronary artery bypass surgery was conducted the following day. He was discharged home 10 days after surgery.
    UNASSIGNED: We describe a successful sequential approach involving the percutaneous repair of a native aortic coarctation followed by a surgical myocardial revascularization in the context of acute coronary syndrome. Discussion within a multidisciplinary Heart Team is key in patients with such complexity.
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  • 文章类型: Case Reports
    患有免疫性血小板减少症的患者的心肌梗死(MI)是一种罕见的情况,管理起来非常困难。
    我们介绍了一例罕见的免疫性血小板减少性紫癜患者,该患者发生双区域段抬高型心源性休克。她的表现极为罕见,主动脉根部有一个新的移动血栓,该血栓阻塞了右冠状动脉口,并延伸到动脉中,并栓塞到左前降支远端。由于悬垂血栓的危险位置,我们保守地管理了该患者,恢复良好,和严重的血小板减少症.
    需要多学科方法来管理已有血液疾病的患者的MI,根据患者的表现和治疗要求定制治疗。
    UNASSIGNED: Myocardial infarction (MI) in a patient with immune thrombocytopenia is a rare scenario which is very challenging to manage.
    UNASSIGNED: We present a rare case of a patient with immune thrombocytopenic purpura who developed double territory segment-elevation MI with cardiogenic shock. She had an extremely rare presentation with a fresh mobile thrombus in the aortic root which was trap-dooring the right coronary artery ostium and extending into the artery with an embolism into the distal left anterior descending artery. We managed this patient conservatively with excellent recovery owing to the dangerous location of the hanging thrombus, and severe thrombocytopenia.
    UNASSIGNED: Multidisciplinary approach is required for the management of MI in patients with pre-existing blood disorders, with therapy tailored to the patient\'s presentation and treatment requirements.
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  • 文章类型: Case Reports
    背景:急性心肌梗死(AMI)后,左心室游离壁破裂(LVFWR)和室间隔破裂(VSR)的手术具有很高的住院死亡率,随着时间的推移,这种情况没有显著改善。卸载LV对于防止修复部位的过度压力和避免出血等问题至关重要。泄漏,贴片开裂,和LVFWR和VSR复发,因为组织是如此脆弱。我们介绍了2例AMI机械并发症急诊手术后使用Impella5.5进行LV卸载的患者。
    方法:一名76岁男性STEMI患者接受了右冠状动脉远端纤溶。三天后,他昏倒了,休克了。超声心动图显示心脏压塞。我们在后外侧壁上发现了渗出型LVFWR,并使用TachoSil进行了非缝合技术处理。在患者离开CPB之前,通过连接到右腋窝动脉的IOmm合成移植物将Impella5.5插入LV。我们将流速保持在4.0至4.5L/min以上,直到POD3以降低LV壁张力,同时最小化搏动性。在POD6上,我们将患者从Impella5.5断奶。术后心脏CT扫描显示LV没有造影剂渗漏。然而,肝素给药期间POD4的脑出血使他住院复杂化。病例2:诊断为由STEMI引起的心源性休克发生在一名84岁男性患者中,在IABP支持下接受LADPCI的患者。PCI术后3天超声心动图显示VSR,患者接受了紧急VSR修复,使用两个单独的贴片,并将BioGlue应用于它们之间的缝合线。在从CPB断奶之前,我们在LV中植入了Impella5.5,并增加了静脉动脉体外膜氧合(VA-ECMO)支持右心衰竭。术后超声心动图显示无残余分流。
    结论:因AMI机械并发症而接受急诊手术的患者可能会发现Impella5.5是左心室卸载的有效工具。与Impella联合使用VA-ECMO可能是管理与并发右侧心力衰竭相关的VSR的有效策略。
    BACKGROUND: Following an acute myocardial infarction (AMI), surgery for left ventricular free wall rupture (LVFWR) and ventricular septal rupture (VSR) has a high in-hospital mortality rate, which has not improved significantly over time. Unloading the LV is critical to preventing excessive stress on the repair site and avoiding problems such as bleeding, leaks, patch dehiscence, and recurrence of LVFWR and VSR because the tissue is so fragile. We present two cases of patients who used Impella 5.5 for LV unloading following emergency surgery for AMI mechanical complications.
    METHODS: A 76-year-old male STEMI patient underwent fibrinolysis of the distal right coronary artery. Three days later, he passed out and went into shock. Echocardiography revealed a cardiac tamponade. We found an oozing-type LVFWR on the posterolateral wall and treated it with a non-suture technique using TachoSil. Before the patient was taken off CPB, Impella 5.5 was inserted into the LV via a 10 mm synthetic graft connected to the right axillary artery. We kept the flow rate above 4.0 to 4.5 L/min until POD 3 to reduce LV wall tension while minimizing pulsatility. On POD 6, we weaned the patient from Impella 5.5. A postoperative cardiac CT scan showed no contrast leakage from the LV. However, a cerebral hemorrhage on POD 4 during heparin administration complicated his hospitalization. Case 2: A diagnosis of cardiogenic shock caused by STEMI occurred in an 84-year-old male patient, who underwent PCI of the LAD with IABP support. Three days after PCI, echocardiography revealed VSR, and the patient underwent emergency VSR repair with two separate patches and BioGlue applied to the suture line between them. Before weaning from CPB, we implanted Impella 5.5 in the LV and added venoarterial extracorporeal membrane oxygenation (VA-ECMO) support for right heart failure. The postoperative echocardiography revealed no residual shunt.
    CONCLUSIONS: Patients undergoing emergency surgery for mechanical complications of AMI may find Impella 5.5 to be an effective tool for LV unloading. The use of VA-ECMO in conjunction with Impella may be an effective strategy for managing VSR associated with concurrent right-sided heart failure.
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  • 文章类型: Case Reports
    干勺,一种相当危险的行为,即食用未稀释的锻炼前蛋白粉,希望能有更明显的能量激增,正日益成为全球健身趋势。一位以前健康的25岁非洲裔男子表现为急性发作的胸骨中期胸痛4小时。他的症状在健身房完成2小时的锻炼方案后约一个小时开始。他的既往病史并不明显,除了8个月的锻炼前补充剂作为他的健身房常规的一部分。他声称已经遵守了制造商推荐的使用补充剂的方法,除了在演示前3天,当他开始“干sc”后,观看了他的健身WhatsApp小组倡导这种做法的视频。心脏评估显示了与前外侧ST抬高型心肌梗死诊断一致的特征。急诊冠状动脉造影显示血栓性病变完全阻塞了近端左前降支冠状动脉,远端有TIMI0流量。成功的球囊血管成形术后,一个药物洗脱支架成功植入,恢复TIMI3流向近端左前降支冠状动脉。本病例报告旨在提高临床医生和公众对锻炼前补充剂普遍性的认识。消费方法不当,以及滥用可能危及生命的后果。
    Dry scooping, a rather risky act of consuming undiluted pre-workout protein powder hoping for a more pronounced energy surge, is increasingly becoming a fitness trend worldwide. A previously healthy 25-year-old man of African origin presented with acute onset of crushing mid-sternal chest pain for 4 h. His symptoms began about an hour following completion of his 2-h exercise regimen at the gym. He had an unremarkable past medical history except for an 8-month consumption of a pre-workout supplement as part of his gym routine. He claimed to have adhered to the manufacturer\'s recommended method of using the supplement, except for 3 days prior to presentation when he started \"dry scooping\" following the viewing of a video advocating such practice from his fitness WhatsApp group. Cardiac evaluation revealed features in keeping with diagnosis of anterolateral ST-elevation myocardial infarction. Emergency coronary angiography revealed a thrombotic lesion completely occluding the proximal left anterior descending coronary artery with TIMI 0 flow distally. After successful balloon angioplasty, a drug-eluting stent was implanted successfully, restoring TIMI 3 flow to the proximal left anterior descending coronary artery. This case report aims to raise awareness among both clinicians and the general public regarding the pervasiveness of pre-workout supplements, improper methods of consumption, and the potential life-threatening repercussions of misuse.
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  • 文章类型: Case Reports
    急性心肌梗死(AMI)是青年患者的重要问题,因为它对健康和社会生活的影响。年轻人的ST抬高型心肌梗死(STEMI)的机制和病程可能与老年人不同。白塞病(BD)是一种病因不明的多系统自身免疫性疾病。心脏受累很少,然而据报道,它影响了6%的患者,17%的病例表现为第一表现。我们介绍了一个33岁的男性重度吸烟者,病史阴性,出现急性下壁心肌梗死.他的冠状动脉造影显示右冠状动脉近端有巨大的血栓形成。他接受了原发性冠状动脉介入治疗和药物洗脱支架植入治疗,随后在48h内因急性支架内血栓形成而介入并植入另外两个药物洗脱支架。风湿病学评估显示有4次不同的口腔溃疡发作和1次生殖器溃疡发作史。他的检查显示人白细胞抗原(HLA)等位基因(B51)阳性,与BD密切相关。青年动脉血栓形成导致的AMI可归因于与BD早期表现有关的高凝状态。增加年轻人对AMI的认识及其在BD中的表现对于降低发病率和死亡率是必要的。糖皮质激素和秋水仙碱可改善BD的心脏表现。
    Acute myocardial infarction (AMI) in young patients is an important issue because of its impact on health and social life. The mechanisms and disease courses of ST-elevation myocardial infarction (STEMI) in young individuals may differ from those in the elderly. Behcet disease (BD) is a multisystem autoimmune disorder of unknown etiology. Cardiac involvement is rare, yet it was reported to affect 6% of patients, with 17% of the cases presenting as the first manifestation. We present the case of a 33-year-old male heavy smoker with negative medical history, who presented with acute inferior myocardial infarction. His coronary angiography showed huge thrombosis in proximal right coronary artery. He was treated with primary coronary intervention and implantation of drug-eluting stent, with subsequent intervention and implantation of two more drug-eluting stents due to acute stent thrombosis within 48 h. Rheumatologic assessment revealed the history of four different attacks of oral ulcers and one attack of genital ulcer. His workup showed positive human leukocyte antigen (HLA) allele (B51) which is strongly associated with BD. AMI in young adults due to arterial thrombosis can be attributed to hypercoagulable state related to early manifestation of BD. Increased knowledge of AMI in young adults and its presentation in BD is necessary to reduce morbidity and mortality. Corticosteroids and colchicine may improve cardiac manifestations in BD.
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