•炎性肌纤维母细胞瘤(IMT)倾向于局部复发,但很少转移。•IMT倾向于局部复发,但很少转移。•不表达间变性淋巴瘤激酶(ALK)的IMT预后较差。•目前ALK靶向疗法的试验显示了治疗这种肿瘤的前景。
•Inflammatory myofibroblastic tumor (IMT) tends to locally recur but rarely metastasizes.•IMT tends to locally recur but rarely metastasizes.•IMTs that do not express anaplastic lymphoma kinase (ALK) have worse prognosis.•Current trials for ALK targeted therapies show promise in treating this neoplasm.