在着色性干皮病衍生的成纤维细胞中 , 被烷基化致癌物破坏的 DNA 修复存在缺陷。
Mesh : Alkylating Agents / pharmacology Carcinogens Cell Division DNA / metabolism DNA Repair Ethylnitrosourea / pharmacology Fibroblasts / drug effects Guanine Nucleotides / metabolism Humans Kinetics Methylnitrosourea / pharmacology Nitrosourea Compounds / pharmacology Xeroderma Pigmentosum / metabolism