Abstract：
OBJECTIVE: To evaluate the predictive value of anterior segment optical coherence tomography (AS-OCT) for postoperative corneal edema in cataract patients.
METHODS: A retrospective cohort study of 144 cataract patients from December 2020 to December 2021 was conducted. Patients were divided into edema eyes (84 cases) and observation (60 cases) group based on postoperative corneal edema occurrence. Relevant indicators were compared between groups. Logistic regression identified risk factors for postoperative corneal edema. Receiver operating characteristic curves evaluated the predictive value.
RESULTS: The edema eyes group had significantly higher postoperative central corneal thickness (CCT) and lower postoperative endothelial cell density (ECD) than the observation group (P < 0.05). The edema eyes group also had significantly lower preoperative ECD, anterior chamber depth (ACD), anterior chamber angle (ACA), and preoperative lens position (LP) than the observation group (P < 0.05). Logistic regression analysis showed that preoperative ECD, ACD, ACA, and LP were independent risk factors for postoperative corneal edema (P < 0.05), all of which also showed good predictive value for postoperative corneal edema, with areas under the curve (AUCs) of 0.854, 0.812, 0.791, and 0.778, respectively, under the ROC curve analysis.
CONCLUSIONS: AS-OCT can provide useful information for predicting postoperative corneal edema in cataract patients. Preoperative ECD, preoperative ACD, preoperative ACA, and preoperative LP are important parameters that can be measured by AS-OCT and used as risk factors for postoperative corneal edema.
METHODS: A retrospective cohort study of 144 cataract patients from December 2020 to December 2021 was conducted. Patients were divided into edema eyes (84 cases) and observation (60 cases) group based on postoperative corneal edema occurrence. Relevant indicators were compared between groups. Logistic regression identified risk factors for postoperative corneal edema. Receiver operating characteristic curves evaluated the predictive value.
RESULTS: The edema eyes group had significantly higher postoperative central corneal thickness (CCT) and lower postoperative endothelial cell density (ECD) than the observation group (P < 0.05). The edema eyes group also had significantly lower preoperative ECD, anterior chamber depth (ACD), anterior chamber angle (ACA), and preoperative lens position (LP) than the observation group (P < 0.05). Logistic regression analysis showed that preoperative ECD, ACD, ACA, and LP were independent risk factors for postoperative corneal edema (P < 0.05), all of which also showed good predictive value for postoperative corneal edema, with areas under the curve (AUCs) of 0.854, 0.812, 0.791, and 0.778, respectively, under the ROC curve analysis.
CONCLUSIONS: AS-OCT can provide useful information for predicting postoperative corneal edema in cataract patients. Preoperative ECD, preoperative ACD, preoperative ACA, and preoperative LP are important parameters that can be measured by AS-OCT and used as risk factors for postoperative corneal edema.
摘要：
目的：评价眼前节光学相干断层扫描（AS-OCT）对白内障患者术后角膜水肿的预测价值。
方法：对2020年12月至2021年12月144例白内障患者进行了回顾性队列研究。根据术后角膜水肿的发生情况分为水肿眼84例和观察眼60例。组间比较相关指标。Logistic回归分析确定术后角膜水肿的危险因素。接收器工作特征曲线评估预测值。
结果：水肿眼组术后中央角膜厚度（CCT）明显高于观察组，术后内皮细胞密度（ECD）明显低于观察组（P<0.05）。水肿眼组的术前ECD也明显降低，前房深度（ACD），前房角(ACA),术前晶状体位置(LP)优于观察组(P<0.05)。Logistic回归分析显示,术前,ACD,ACA,和LP是术后角膜水肿的独立危险因素(P<0.05),所有这些都对术后角膜水肿具有良好的预测价值，曲线下面积（AUC）分别为0.854、0.812、0.791和0.778，下ROC曲线分析。
结论：AS-OCT可以为预测白内障患者术后角膜水肿提供有用的信息。术前ECD,术前ACD,术前ACA,术前LP是可以通过AS-OCT测量的重要参数，并用作术后角膜水肿的危险因素。
方法：对2020年12月至2021年12月144例白内障患者进行了回顾性队列研究。根据术后角膜水肿的发生情况分为水肿眼84例和观察眼60例。组间比较相关指标。Logistic回归分析确定术后角膜水肿的危险因素。接收器工作特征曲线评估预测值。
结果：水肿眼组术后中央角膜厚度（CCT）明显高于观察组，术后内皮细胞密度（ECD）明显低于观察组（P<0.05）。水肿眼组的术前ECD也明显降低，前房深度（ACD），前房角(ACA),术前晶状体位置(LP)优于观察组(P<0.05)。Logistic回归分析显示,术前,ACD,ACA,和LP是术后角膜水肿的独立危险因素(P<0.05),所有这些都对术后角膜水肿具有良好的预测价值，曲线下面积（AUC）分别为0.854、0.812、0.791和0.778，下ROC曲线分析。
结论：AS-OCT可以为预测白内障患者术后角膜水肿提供有用的信息。术前ECD,术前ACD,术前ACA,术前LP是可以通过AS-OCT测量的重要参数，并用作术后角膜水肿的危险因素。
