PDF(Pubmed)
Abstract：
Little is known about the prevalence of incapacitating substances present in drug facilitated sexual assaults (DFSA). Presented here is a literature review conducted to provide background information, such as symptoms, exacerbations, and drug interactions, on drugs typically implicated in DFSA, namely gamma-hydroxybutyrate (GHB), gamma-butyrolactone (GBL), 1,4-butanediol (1,4-BD), ketamine, diazepam, oxycodone, methamphetamine, and alcohol. Literature found through Scopus and Pubmed was reviewed to determine the current prevalence of these substances in DFSA with a focus on Australian data. The global literature revealed that there is a wide variety of substances used in DFSA and the prevalence varied by country. For example, it was found that in Northern Ireland, opioids were most prevalent whereas in France, benzodiazepines were most prevalent. In Australia the review revealed a lack of contemporary data with the most recent report in Victoria using data collected during 2011-2013. The literature also revealed there can be an important difference between self-reported substance use and substances discovered via toxicological analysis. This can be due to the challenges of biological detection, reliability of self-reporting, and the possibility of a substance being introduced to a person\'s food or drink without their knowledge. This review highlights the need for the collection and analysis of current data pertaining to DFSA reports and the drugs detected, and due to the constantly evolving picture of both licit and illicit drug use an assessment of the role of prescription medications in DFSA due to drug-drug interactions as well as potential to incapacitate is warranted.
摘要：
对药物促进的性侵犯（DFSA）中存在的无行为能力物质的流行知之甚少。这里提出了一个文献综述，以提供背景信息，如症状，恶化,和药物相互作用，关于典型地涉及DFSA的药物，即γ-羟基丁酸酯（GHB），γ-丁内酯(GBL),1,4-丁二醇(1,4-BD),氯胺酮,地西泮,羟考酮,甲基苯丙胺,和酒精。通过Scopus和Pubmed发现的文献进行了审查，以确定这些物质在DFSA中的当前患病率，重点是澳大利亚数据。全球文献显示，DFSA中使用的物质种类繁多，流行程度因国家而异。例如,在北爱尔兰,阿片类药物最普遍，而在法国，苯二氮卓类药物最普遍。在澳大利亚，审查显示缺乏当代数据，维多利亚州的最新报告使用了2011-2013年期间收集的数据。文献还表明，自我报告的物质使用与通过毒理学分析发现的物质之间可能存在重要差异。这可能是由于生物检测的挑战，自我报告的可靠性，以及一种物质在他们不知情的情况下被引入到一个人的食物或饮料中的可能性。这篇综述强调需要收集和分析与DFSA报告和检测到的药物有关的当前数据，并且由于合法和非法药物使用的情况不断变化，因此有必要评估由于药物-药物相互作用以及丧失行为能力的可能性而导致的处方药在DFSA中的作用。
