PDF(Pubmed)
Abstract：
UNASSIGNED: The lack of physical activity is a common issue in modern society and is considered a major risk factor for various chronic non-communicable diseases. Bioactive factors secreted by skeletal muscle during exercise play a crucial role in inter-organ interactions. Since the concept of \"myokines\" was proposed in 2004, hundreds of regulatory myokines have been identified. Visual analysis of research on exercise-regulated myokines is significant to explore research hotspots and frontiers in this field.
UNASSIGNED: Research literature on exercise-regulated myokines from 2003 to 2023 in the \"Web of Science\" database was used as the data source. Knowledge maps were drawn using \"VOS Viewer, CiteSpace, and R-bibliometrix\" software.
UNASSIGNED: A total of 1,405 papers were included, showing a fluctuating yet slow growth in annual publications. The United States and China led in the number of publications and collaboration networks. Harvard University ranked first with 120 publications. CIBER (centrality 0.16) and the University of California System (centrality 0.16) were pivotal in advancing this field. PEDERSEN BK led author rankings with 41 publications and 1,952 citations. FRONTIERS IN PHYSIOLOGY ranked first among journals with 64 publications and the highest g-index (39), while PLoS One had the highest h-index (25) and most citations (2,599). Key co-cited reference clusters included #1 skeletal muscle dysfunction, #2 obesity, #6 ASCs, and #7 adaptive immunocytes. Pontus Boström\'s paper had a notable citation burst intensity of 77.37. High-frequency keywords were \"exercise\" (509), \"skeletal muscle\" (452), and \"expression\" (293), with long-term keywords such as #0 irisin, #2 insulin resistance, #3 transcription, and #6 physical activity. Recently, keywords like \"physical exercise,\" \"resistance exercise,\" \"aerobic exercise,\" \"insulin,\" and \"oxidative stress\" have emerged.
UNASSIGNED: Research in the field of exercise-regulated myokines shows an overall upward trend. The focus areas include myokines mediated by different types of exercise, the interaction of irisin-mediated muscle with other organs, and the important role of myokine-mediated oxidative stress in exercise simulation.
UNASSIGNED: Research literature on exercise-regulated myokines from 2003 to 2023 in the \"Web of Science\" database was used as the data source. Knowledge maps were drawn using \"VOS Viewer, CiteSpace, and R-bibliometrix\" software.
UNASSIGNED: A total of 1,405 papers were included, showing a fluctuating yet slow growth in annual publications. The United States and China led in the number of publications and collaboration networks. Harvard University ranked first with 120 publications. CIBER (centrality 0.16) and the University of California System (centrality 0.16) were pivotal in advancing this field. PEDERSEN BK led author rankings with 41 publications and 1,952 citations. FRONTIERS IN PHYSIOLOGY ranked first among journals with 64 publications and the highest g-index (39), while PLoS One had the highest h-index (25) and most citations (2,599). Key co-cited reference clusters included #1 skeletal muscle dysfunction, #2 obesity, #6 ASCs, and #7 adaptive immunocytes. Pontus Boström\'s paper had a notable citation burst intensity of 77.37. High-frequency keywords were \"exercise\" (509), \"skeletal muscle\" (452), and \"expression\" (293), with long-term keywords such as #0 irisin, #2 insulin resistance, #3 transcription, and #6 physical activity. Recently, keywords like \"physical exercise,\" \"resistance exercise,\" \"aerobic exercise,\" \"insulin,\" and \"oxidative stress\" have emerged.
UNASSIGNED: Research in the field of exercise-regulated myokines shows an overall upward trend. The focus areas include myokines mediated by different types of exercise, the interaction of irisin-mediated muscle with other organs, and the important role of myokine-mediated oxidative stress in exercise simulation.
摘要：
■缺乏体育锻炼是现代社会的常见问题，被认为是各种慢性非传染性疾病的主要危险因素。运动过程中骨骼肌分泌的生物活性因子在器官间相互作用中起着至关重要的作用。自2004年提出“Myokines”概念以来，已经发现了数百种调节性Myokines。可视化分析运动调节型肌细胞的研究对于探索该领域的研究热点和前沿具有重要意义。
■使用“WebofScience”数据库中2003年至2023年关于运动调节的肌细胞的研究文献作为数据源。使用“VOSViewer”绘制了知识图，CiteSpace,和R-bibliometrix软件。
■共收录了1,405篇论文，显示出年度出版物的波动但缓慢增长。美国和中国在出版物和合作网络的数量方面处于领先地位。哈佛大学以120种出版物排名第一。CIBER（中心性0.16）和加州大学系统（中心性0.16）在推进这一领域方面至关重要。PEDERSENBK以41种出版物和1,952种引文引领作者排名。《生理学》杂志排名第一，有64篇出版物和最高的g指数（39），而PLoSOne的h指数最高(25)，引用次数最多(2599)。关键的共同引用的参考集群包括#1骨骼肌功能障碍，#2肥胖，#6ASCs,和#7适应性免疫细胞。PontusBoström的论文的引文爆发强度为77.37。高频关键词是“锻炼”(509)，“骨骼肌”（452），和“表达式”(293)，使用长期关键字，如#0irisin，#2胰岛素抵抗,#3转录，#6体力活动最近,关键词如“体育锻炼，“\”阻力练习，“\”有氧运动，胰岛素，“和”氧化应激“已经出现。
■运动调节型肌细胞领域的研究显示出总体上升趋势。重点领域包括由不同类型的运动介导的肌细胞，irisin介导的肌肉与其他器官的相互作用，以及肌肉因子介导的氧化应激在运动模拟中的重要作用。
■使用“WebofScience”数据库中2003年至2023年关于运动调节的肌细胞的研究文献作为数据源。使用“VOSViewer”绘制了知识图，CiteSpace,和R-bibliometrix软件。
■共收录了1,405篇论文，显示出年度出版物的波动但缓慢增长。美国和中国在出版物和合作网络的数量方面处于领先地位。哈佛大学以120种出版物排名第一。CIBER（中心性0.16）和加州大学系统（中心性0.16）在推进这一领域方面至关重要。PEDERSENBK以41种出版物和1,952种引文引领作者排名。《生理学》杂志排名第一，有64篇出版物和最高的g指数（39），而PLoSOne的h指数最高(25)，引用次数最多(2599)。关键的共同引用的参考集群包括#1骨骼肌功能障碍，#2肥胖，#6ASCs,和#7适应性免疫细胞。PontusBoström的论文的引文爆发强度为77.37。高频关键词是“锻炼”(509)，“骨骼肌”（452），和“表达式”(293)，使用长期关键字，如#0irisin，#2胰岛素抵抗,#3转录，#6体力活动最近,关键词如“体育锻炼，“\”阻力练习，“\”有氧运动，胰岛素，“和”氧化应激“已经出现。
■运动调节型肌细胞领域的研究显示出总体上升趋势。重点领域包括由不同类型的运动介导的肌细胞，irisin介导的肌肉与其他器官的相互作用，以及肌肉因子介导的氧化应激在运动模拟中的重要作用。
