PDF(Pubmed)
Abstract：
Malignant transformation (MCT) of ovary is rare complications affecting elderly, squamous cell carcinoma being the most common. The prognosis worsens with extraovarian spread. We present two cases of MCT-derived SCC. Patients exhibited abdominal lump, pain, bowel symptoms, sometimes with weight loss; imaging revealed MCT. Age (51-60), postmenopausal status, large size (>20 cm), bilaterality, and complex ovarian lesions raised suspicion of malignancy. Elevated tumor markers (e.g., cancer antigen-125 and lactate dehydrogenase) were noted in one case. Intraoperative frozen section confirmed malignancy, guiding staging laparotomy. One case was advanced stage on histopathology. Intraoperative frozen section aids optimal staging.
摘要：
卵巢恶变（MCT）是影响老年人的罕见并发症，鳞状细胞癌是最常见的。卵巢外扩散预后恶化。我们介绍了两例MCT衍生的SCC。患者出现腹部肿块，疼痛,肠道症状,有时体重减轻；影像学显示MCT。年龄（51-60岁）绝经后状态，大尺寸（>20厘米），双边性，和复杂的卵巢病变引起恶性肿瘤的怀疑。升高的肿瘤标志物(例如，在一例中注意到癌症抗原125和乳酸脱氢酶）。术中冰冻切片证实为恶性肿瘤，引导分期剖腹手术。1例组织病理学晚期。术中冰冻切片有助于最佳分期。
