PDF(Pubmed)
Abstract：
UNASSIGNED: In patients with schizophrenia spectrum disorder (SSD), the lifetime prevalence of self-harm (SH) and non-suicidal self-injury (NSSI) is currently uncertain. The primary aim of this review was to provide a synthesis of the existing literature concerning the prevalence of SH/NSSI in individuals with SSD, and individuals at clinical high risk of psychosis (CHR-P). Secondary aims were to investigate methods, severity, and functions of self-injurious behavior in these populations.
UNASSIGNED: Studies quantifying the prevalence of SH/NSSI in individuals with SSD or at CHR-P were included in this review. MEDLINE, EMBASE, and PsycInfo were searched for eligible studies June 10, 2022 and systematically screened by two independent reviewers. Risk of bias was assessed using the Joana Briggs Institute Critical Appraisal Checklist for Prevalence Studies by two independent reviewers. A meta-analysis of the lifetime prevalence of SH/NSSI was conducted using generalized linear mixed model with the logit transformation.
UNASSIGNED: Thirty-two studies were included in this review (n = 15 440), 4 of which included individuals at CHR-P (n = 397). The meta-analysis showed a pooled lifetime prevalence of SH of 31.0% (95% CI: 22.1%; 41.6%) in individuals with SSD (n = 2822) and 39.7% (95% CI: 17.5%; 70.0%) in individuals at CHR-P (n = 397). These estimates should be interpreted with caution due to substantial heterogeneity. Cutting was the most frequent method of SH/NSSI and SH command hallucinations may be an overlooked cause of self-injurious behavior in these patients.
UNASSIGNED: Self-injurious behavior is a highly prevalent, and possibly overlooked concern, in individuals with SSD and at CHR-P.
UNASSIGNED: Studies quantifying the prevalence of SH/NSSI in individuals with SSD or at CHR-P were included in this review. MEDLINE, EMBASE, and PsycInfo were searched for eligible studies June 10, 2022 and systematically screened by two independent reviewers. Risk of bias was assessed using the Joana Briggs Institute Critical Appraisal Checklist for Prevalence Studies by two independent reviewers. A meta-analysis of the lifetime prevalence of SH/NSSI was conducted using generalized linear mixed model with the logit transformation.
UNASSIGNED: Thirty-two studies were included in this review (n = 15 440), 4 of which included individuals at CHR-P (n = 397). The meta-analysis showed a pooled lifetime prevalence of SH of 31.0% (95% CI: 22.1%; 41.6%) in individuals with SSD (n = 2822) and 39.7% (95% CI: 17.5%; 70.0%) in individuals at CHR-P (n = 397). These estimates should be interpreted with caution due to substantial heterogeneity. Cutting was the most frequent method of SH/NSSI and SH command hallucinations may be an overlooked cause of self-injurious behavior in these patients.
UNASSIGNED: Self-injurious behavior is a highly prevalent, and possibly overlooked concern, in individuals with SSD and at CHR-P.
摘要：
■在精神分裂症谱系障碍（SSD）患者中，自残(SH)和非自杀性自伤(NSSI)的终生患病率目前尚不确定.本综述的主要目的是提供有关SSD个体中SH/NSSI患病率的现有文献的综合。和临床精神病高危人群（CHR-P）。次要目的是研究方法，严重程度,以及这些人群中自我伤害行为的功能。
■本综述包括量化患有SSD或CHR-P的个体中SH/NSSI患病率的研究。MEDLINE,EMBASE,和PsycInfo在2022年6月10日搜索了符合条件的研究,并由两名独立评审员进行了系统筛选.由两名独立的审查员使用JoanaBriggs研究所的患病率研究关键评估清单评估偏倚风险。使用带有Logit变换的广义线性混合模型对SH/NSSI的终生患病率进行荟萃分析。
■本综述包括32项研究（n=15440），其中4名包括CHR-P个体(n=397)。荟萃分析显示，患有SSD的个体（n=2822）和CHR-P的个体（n=397）中SH的合并终生患病率为31.0%（95%CI：22.1%；41.6%），为39.7%（95%CI：17.5%；70.0%）。由于大量的异质性，这些估计应谨慎解释。切割是SH/NSSI最常见的方法，SH命令幻觉可能是这些患者自伤行为的一个被忽视的原因。
■自我伤害行为是一种非常普遍的行为，可能被忽视的担忧，在具有SSD和CHR-P的个人中
■本综述包括量化患有SSD或CHR-P的个体中SH/NSSI患病率的研究。MEDLINE,EMBASE,和PsycInfo在2022年6月10日搜索了符合条件的研究,并由两名独立评审员进行了系统筛选.由两名独立的审查员使用JoanaBriggs研究所的患病率研究关键评估清单评估偏倚风险。使用带有Logit变换的广义线性混合模型对SH/NSSI的终生患病率进行荟萃分析。
■本综述包括32项研究（n=15440），其中4名包括CHR-P个体(n=397)。荟萃分析显示，患有SSD的个体（n=2822）和CHR-P的个体（n=397）中SH的合并终生患病率为31.0%（95%CI：22.1%；41.6%），为39.7%（95%CI：17.5%；70.0%）。由于大量的异质性，这些估计应谨慎解释。切割是SH/NSSI最常见的方法，SH命令幻觉可能是这些患者自伤行为的一个被忽视的原因。
■自我伤害行为是一种非常普遍的行为，可能被忽视的担忧，在具有SSD和CHR-P的个人中
