Abstract：
BACKGROUND: Migraine is a prevalent episodic headache that affects approximately 14%-15% of the global population. Since valsartan is an antihypertensive drug, it is hypothesized that taking valsartan can prevent migraine attacks in patients with the condition. This study aimed to determine the efficacy of propranolol versus valsartan in preventing migraine attacks.
METHODS: This randomized controlled trial was conducted on 56 patients with migraine from a neurology clinic. Patients were divided into two equal groups of 28 individuals, after providing informed consent. The patients then received either propranolol or valsartan treatment. The intensity and frequency of migraines were compared before and after treatment in both study groups.
RESULTS: The patients\' mean age was 32.78 years old (±6.9 SD), and 64% of the patients were female. After a 1-month treatment period, the results showed that valsartan patients experienced significantly fewer severe migraine attacks compared to propranolol patients.
CONCLUSIONS: According to the results of the present study, valsartan may be at least as effective as propranolol and perhaps more effective on some measures.
METHODS: This randomized controlled trial was conducted on 56 patients with migraine from a neurology clinic. Patients were divided into two equal groups of 28 individuals, after providing informed consent. The patients then received either propranolol or valsartan treatment. The intensity and frequency of migraines were compared before and after treatment in both study groups.
RESULTS: The patients\' mean age was 32.78 years old (±6.9 SD), and 64% of the patients were female. After a 1-month treatment period, the results showed that valsartan patients experienced significantly fewer severe migraine attacks compared to propranolol patients.
CONCLUSIONS: According to the results of the present study, valsartan may be at least as effective as propranolol and perhaps more effective on some measures.
摘要：
背景：偏头痛是一种普遍的偶发性头痛，影响约14%-15%的全球人口。由于缬沙坦是一种抗高血压药物，据推测，服用缬沙坦可以预防患有这种疾病的患者的偏头痛发作。本研究旨在确定普萘洛尔与缬沙坦预防偏头痛发作的疗效。
方法：这项随机对照试验是对神经科诊所的56名偏头痛患者进行的。患者被分为两组，每组28人，在提供知情同意后。然后患者接受普萘洛尔或缬沙坦治疗。比较两组患者治疗前后偏头痛的强度和频率。
结果：患者的平均年龄为32.78岁（±6.9SD），64%的患者为女性。经过1个月的治疗期，结果显示，与普萘洛尔患者相比，缬沙坦患者的严重偏头痛发作明显较少。
结论：根据本研究的结果，缬沙坦可能至少与普萘洛尔一样有效，并且在某些措施中可能更有效。
方法：这项随机对照试验是对神经科诊所的56名偏头痛患者进行的。患者被分为两组，每组28人，在提供知情同意后。然后患者接受普萘洛尔或缬沙坦治疗。比较两组患者治疗前后偏头痛的强度和频率。
结果：患者的平均年龄为32.78岁（±6.9SD），64%的患者为女性。经过1个月的治疗期，结果显示，与普萘洛尔患者相比，缬沙坦患者的严重偏头痛发作明显较少。
结论：根据本研究的结果，缬沙坦可能至少与普萘洛尔一样有效，并且在某些措施中可能更有效。
