Abstract：
Surgery of jawbones has a high potential risk of causing complications associated with temporomandibular joint disorder (TMD). The objective of this study was to investigate the effects of two drive modeling methods on the biomechanical behavior of the temporomandibular joint (TMJ) including articular disc during mandibular movements. A finite element (FE) model from a healthy human computed tomography was used to evaluate TMJ dynamic using two methods, namely, a conventional spatial-oriented method (displacement-driven) and a compliant muscle-initiated method (masticatory muscle-driven). The same virtual FE model was 3D printed and a custom designed experimental platform was established to validate the accuracy of experimental and theoretical results of the TMJ biomechanics during mandibular movements. The results show that stress distributed to TMJ and articular disc from mandibular movements provided better representation from the muscle-driving approach than those of the displacement-driven modeling. The simulation and experimental data exhibited significant strong correlations during opening, protrusion, and laterotrusion (with canonical correlation coefficients of 0.994, 0.993, and 0.932, respectively). The use of muscle-driven modeling holds promise for more accurate forecasting of stress analysis of TMJ and articular disc during mandibular movements. The compliant approach to analyze TMJ dynamics would potentially contribute to clinic diagnosis and prediction of TMD resulting from occlusal disease and jawbone surgery such as orthognathic surgery or tumor resection.
摘要：
下颌骨手术具有引起与颞下颌关节紊乱（TMD）相关的并发症的高潜在风险。这项研究的目的是研究两种驱动建模方法对下颌运动过程中包括关节盘在内的颞下颌关节（TMJ）生物力学行为的影响。来自健康人体计算机断层扫描的有限元（FE）模型用于使用两种方法评估TMJ动态，即,传统的空间导向方法（位移驱动）和顺应性肌肉启动方法（咀嚼肌肉驱动）。通过3D打印相同的虚拟有限元模型，并建立了自定义设计的实验平台，以验证下颌关节运动过程中TMJ生物力学实验和理论结果的准确性。结果表明，下颌运动分配给TMJ和关节盘的应力比位移驱动模型提供了更好的肌肉驱动方法表示。模拟和实验数据在打开过程中表现出明显的强相关性，突出,和侧向回归(典型相关系数分别为0.994、0.993和0.932)。使用肌肉驱动模型有望更准确地预测下颌运动过程中TMJ和关节盘的应力分析。分析TMJ动力学的合规方法可能有助于临床诊断和预测由咬合疾病和颌骨手术（例如正颌手术或肿瘤切除术）引起的TMD。
