Abstract：
Quaternary phosphonium salts, a significant category of organophosphorus compounds, have garnered substantial attention from chemists due to their wide range of applications across various research areas. These compounds are utilized in organic synthesis, catalysis, medicinal chemistry, natural materials, and coordination chemistry. Their versatility and effectiveness in these fields make them valuable tools in scientific research. Despite their extensive use in various applications, the potential of quaternary phosphonium compounds as fluorescent agents for revealing latent fingerprints (LFPs) remains largely unexplored, presenting an exciting opportunity for further research and development in forensic science. In this study, we designed molecules that combine the aggregation-induced emission (AIE) chromophore with triphenylphosphine to create a series of novel AIE amphiphiles, namely TPP1, TPP2, and TPP3. Through precise adjustment of the carbon chain length between the phenoxy group and the terminal triphenylphosphine, we were able to finely tune the nanostructures and hydrophobicity of the materials. TPP3 emerged as the optimal candidate, possessing the ideal particle size and hydrophobicity to effectively bind to LFPs, thus enabling efficient fingerprint visualization with enhanced fluorescence upon aggregation. Our findings introduce an innovative approach to fingerprint visualization, offering high selectivity, superior imaging of level 3 structures, and long-term effectiveness (up to 30 days). Additionally, TPP3\'s outstanding performance in imaging level 3 structures of LFPs is beneficial for analyzing incomplete LFPs and identifying individuals. By significantly improving the detection and analysis of LFPs, this approach ensures more accurate and reliable identification, making it invaluable for forensic investigations and security measures. The adaptability of these compounds to various fingerprint surfaces highlights their potential in diverse practical applications, enhancing their utility in both forensic science and security fields. This versatility allows for precise fingerprint visualization across different scenarios, making them a critical tool for advancing biometric and security technologies.
摘要：
季鳞盐，一类重要的有机磷化合物，由于其在各个研究领域的广泛应用，因此引起了化学家的广泛关注。这些化合物用于有机合成，催化作用,药物化学,天然材料,和协调化学。它们在这些领域的多功能性和有效性使它们成为科学研究中的宝贵工具。尽管它们在各种应用中广泛使用，季膦化合物作为揭示潜在指纹（LFP）的荧光剂的潜力仍未被探索，为法医学的进一步研究和发展提供了一个令人兴奋的机会。在这项研究中,我们设计了将聚集诱导发射（AIE）发色团与三苯基膦相结合的分子，以创建一系列新型AIE两亲物，即TPP1、TPP2和TPP3。通过精确调整苯氧基和末端三苯基膦之间的碳链长度，我们能够微调材料的纳米结构和疏水性。TPP3成为最佳候选，具有理想的粒径和疏水性，以有效地结合LFP，从而使有效的指纹可视化与增强荧光聚集。我们的发现为指纹可视化引入了一种创新的方法，提供高选择性，3级结构的卓越成像，和长期有效性（长达30天）。此外,TPP3在LFP3级结构成像中的出色表现有利于分析不完整的LFP和识别个体。通过显著改善LFP的检测和分析，这种方法确保了更准确和可靠的识别，使其对法医调查和安全措施非常有价值。这些化合物对各种指纹表面的适应性突出了它们在各种实际应用中的潜力，提高其在法医学和安全领域的效用。这种多功能性允许跨不同场景的精确指纹可视化，使它们成为推进生物识别和安全技术的关键工具。
