PDF(Pubmed)
Abstract：
UNASSIGNED: Cutaneous melanoma (CM) is a significant contributor to skin cancer-related mortality globally and in Canada. Despite the well-established link between ultraviolet (UV) radiation exposure and skin cancer risk, there remains a gap in population-level interventions and persistent misconceptions about sun exposure and impact of environment on individual behavior.
UNASSIGNED: The current study provides an ecological analysis using latest available data (2011-2017) to define geographic/environmental contributors to the CM landscape in Canada.
UNASSIGNED: Utilizing Canadian Cancer Registry and Canadian Urban Environmental Health Research Consortium data, we analyzed 39,605 CM cases occurring in Canada from 2011 to 2017. Environmental data, including UV radiation, greenspace (normalized difference vegetation index), temperature, heat events, and precipitation was used to evaluate the effect of environment on CM incidence rates across Forward Sortation Area postal codes.
UNASSIGNED: Forward Sortation Areas with increased CM incidence were associated with higher annual average temperature, snowfall, heat events, normalized difference vegetation index, and vitamin D-weighted UV exposure. Conversely, factors associated with decreased incidence included an increased annual highest temperature, rain precipitation, and a longer duration of heat events.
UNASSIGNED: This study is subject to ecological bias and findings should be interpreted with caution.
UNASSIGNED: This study further substantiates associations between specific environmental factors and CM incidence.
UNASSIGNED: The current study provides an ecological analysis using latest available data (2011-2017) to define geographic/environmental contributors to the CM landscape in Canada.
UNASSIGNED: Utilizing Canadian Cancer Registry and Canadian Urban Environmental Health Research Consortium data, we analyzed 39,605 CM cases occurring in Canada from 2011 to 2017. Environmental data, including UV radiation, greenspace (normalized difference vegetation index), temperature, heat events, and precipitation was used to evaluate the effect of environment on CM incidence rates across Forward Sortation Area postal codes.
UNASSIGNED: Forward Sortation Areas with increased CM incidence were associated with higher annual average temperature, snowfall, heat events, normalized difference vegetation index, and vitamin D-weighted UV exposure. Conversely, factors associated with decreased incidence included an increased annual highest temperature, rain precipitation, and a longer duration of heat events.
UNASSIGNED: This study is subject to ecological bias and findings should be interpreted with caution.
UNASSIGNED: This study further substantiates associations between specific environmental factors and CM incidence.
摘要：
■皮肤黑色素瘤（CM）是全球和加拿大皮肤癌相关死亡率的重要因素。尽管紫外线（UV）辐射暴露与皮肤癌风险之间存在着良好的联系，在人群层面的干预措施和对阳光照射和环境对个人行为的影响的持续误解方面仍然存在差距。
■本研究使用最新的可用数据（2011-2017年）提供了生态分析，以定义加拿大CM景观的地理/环境贡献者。
■利用加拿大癌症登记处和加拿大城市环境卫生研究联盟的数据，我们分析了2011年至2017年在加拿大发生的39,605CM病例。环境数据,包括紫外线辐射，绿地(归一化植被指数)，温度,热事件，并使用降水来评估环境对整个正向分拣区邮政编码中CM发病率的影响。
■CM发生率增加的正向分拣区域与较高的年平均温度有关，降雪,热事件，归一化差异植被指数，和维生素D加权紫外线暴露。相反，与发病率下降相关的因素包括年度最高气温升高，降雨,和更长时间的热事件。
■这项研究受到生态偏见的影响，应谨慎解释研究结果。
■本研究进一步证实了特定环境因素与CM发病率之间的关联。
■本研究使用最新的可用数据（2011-2017年）提供了生态分析，以定义加拿大CM景观的地理/环境贡献者。
■利用加拿大癌症登记处和加拿大城市环境卫生研究联盟的数据，我们分析了2011年至2017年在加拿大发生的39,605CM病例。环境数据,包括紫外线辐射，绿地(归一化植被指数)，温度,热事件，并使用降水来评估环境对整个正向分拣区邮政编码中CM发病率的影响。
■CM发生率增加的正向分拣区域与较高的年平均温度有关，降雪,热事件，归一化差异植被指数，和维生素D加权紫外线暴露。相反，与发病率下降相关的因素包括年度最高气温升高，降雨,和更长时间的热事件。
■这项研究受到生态偏见的影响，应谨慎解释研究结果。
■本研究进一步证实了特定环境因素与CM发病率之间的关联。
