PDF(Pubmed)
Abstract：
UNASSIGNED: Weight and waist gain are significant concerns in adulthood. Both weight and waist gain are particularly important among South Asians, known to have an increased risk of developing chronic cardiometabolic complications at any body mass index compared to other racial and ethnic groups. The aim of this study was to investigate factors predicting weight and waist gain in a longitudinal cohort of South Asians living in the US (United States).
UNASSIGNED: This was a prospective analysis using data from exam 1 (2010-2013) and exam 2 (2015-2018) of the Mediators of Atherosclerosis in South Asians Living in America (MASALA) study, a prospective cohort study of South Asians (recruited from San Francisco and Chicago), with a mean 4.8 years of follow-up.
UNASSIGNED: Of 634 participants studied (42.7 % women, mean age 55 years, BMI 25.7 kg/m2, weight 70.4 kg at exam 1), 34.7 % had gained ≥5 % weight and 32.3 % gained ≥5 % waist at exam 2. In the adjusted models, older age, higher number of years of US residence, and having diabetes were associated with lower odds of weight gain; being female and having higher adiponectin were associated with higher odds of weight gain. Being female and being employed full/part time or being retired predicted lower likelihood of waist gain. Being single, separated/divorced, having a higher leptin and a higher C-reactive protein level predicted higher likelihood of waist gain.
UNASSIGNED: The current study identified several social, demographic, and clinical factors that can serve as targets for obesity interventions among US South Asians. In addition, this study also raises hypotheses about associations of adipokine levels with weight and waist gain.
UNASSIGNED: This was a prospective analysis using data from exam 1 (2010-2013) and exam 2 (2015-2018) of the Mediators of Atherosclerosis in South Asians Living in America (MASALA) study, a prospective cohort study of South Asians (recruited from San Francisco and Chicago), with a mean 4.8 years of follow-up.
UNASSIGNED: Of 634 participants studied (42.7 % women, mean age 55 years, BMI 25.7 kg/m2, weight 70.4 kg at exam 1), 34.7 % had gained ≥5 % weight and 32.3 % gained ≥5 % waist at exam 2. In the adjusted models, older age, higher number of years of US residence, and having diabetes were associated with lower odds of weight gain; being female and having higher adiponectin were associated with higher odds of weight gain. Being female and being employed full/part time or being retired predicted lower likelihood of waist gain. Being single, separated/divorced, having a higher leptin and a higher C-reactive protein level predicted higher likelihood of waist gain.
UNASSIGNED: The current study identified several social, demographic, and clinical factors that can serve as targets for obesity interventions among US South Asians. In addition, this study also raises hypotheses about associations of adipokine levels with weight and waist gain.
摘要：
■体重和腰围增长是成年期的重要问题。在南亚人中，体重和腰围的增加尤其重要，已知与其他种族和族裔群体相比，在任何体重指数下发生慢性心脏代谢并发症的风险都增加。这项研究的目的是调查在居住在美国（美国）的南亚人的纵向队列中预测体重和腰围增加的因素。
■这是一项前瞻性分析，使用来自生活在美国的南亚人动脉粥样硬化介质（MASALA）研究的考试1（2010-2013）和考试2（2015-2018）的数据。一项针对南亚人的前瞻性队列研究(从旧金山和芝加哥招募)，平均随访4.8年。
■在634名参与者中（42.7%为女性，平均年龄55岁,BMI25.7kg/m2，检查1时体重70.4kg），在检查2时，34.7%的人体重增加≥5%，32.3%的人增加≥5%的腰围。在调整后的模型中，年龄较大,更多的美国居住年数，糖尿病患者与较低的体重增加几率相关;女性和较高脂联素患者与较高的体重增加几率相关.女性，全职/兼职工作或退休预测腰围增加的可能性较低。单身,分居/离婚,具有较高的瘦素和较高的C反应蛋白水平的人预测腰围增加的可能性较高。
■当前的研究确定了几个社会，人口统计学,以及可以作为美国南亚人肥胖干预目标的临床因素。此外,这项研究还提出了有关脂肪因子水平与体重和腰围增加相关的假设。
■这是一项前瞻性分析，使用来自生活在美国的南亚人动脉粥样硬化介质（MASALA）研究的考试1（2010-2013）和考试2（2015-2018）的数据。一项针对南亚人的前瞻性队列研究(从旧金山和芝加哥招募)，平均随访4.8年。
■在634名参与者中（42.7%为女性，平均年龄55岁,BMI25.7kg/m2，检查1时体重70.4kg），在检查2时，34.7%的人体重增加≥5%，32.3%的人增加≥5%的腰围。在调整后的模型中，年龄较大,更多的美国居住年数，糖尿病患者与较低的体重增加几率相关;女性和较高脂联素患者与较高的体重增加几率相关.女性，全职/兼职工作或退休预测腰围增加的可能性较低。单身,分居/离婚,具有较高的瘦素和较高的C反应蛋白水平的人预测腰围增加的可能性较高。
■当前的研究确定了几个社会，人口统计学,以及可以作为美国南亚人肥胖干预目标的临床因素。此外,这项研究还提出了有关脂肪因子水平与体重和腰围增加相关的假设。
