Abstract：
UNASSIGNED: The aim of this study is to investigate the clinical outcomes of transforaminal lumbar endoscopic discectomy (TLED) in patients with L5-S1 lumbar disc herniation (LDH).
UNASSIGNED: Seventy-five consecutive individuals with diagnosed foraminal/extraforaminal L5-S1 LDH were included in this study. All patients underwent TLED, being subsequently evaluated in a 2-year follow-up period. Assessment was performed preoperatively and at 6 weeks and 3, 6, 12 and 24 months postoperatively. Visual Analogue Scale (distinctly applied for lower limb - VAS-LP and low back - VAS-BP pain) and Short-Form 36 (SF-36) Medical Health Survey Questionnaire were implemented to assess pain and health-related quality of life (HRQoL) of enrolled individuals, respectively.
UNASSIGNED: No major perioperative complications were observed. Recorded values of all studied indices were demonstrated to feature a clinically and statistically significant amelioration at 6 weeks, presenting lesser improvement at 3 months with subsequent stabilisation. VAS-LP and VAS-BP values were displayed to reach a plateau in 6 months postoperatively, whereas all parameters of SF-36 continued to present a statistically significant improvement until the end of follow-up at 2 years.
UNASSIGNED: TLED represent a safe and efficient technique in terms of diminishing perceived pain and improving HRQoL in patients with L5-S1 LDHs. However, specific patient- and technique-related circumstances on the ground of low surgical experience may limit its effectiveness in these patients.
UNASSIGNED: Seventy-five consecutive individuals with diagnosed foraminal/extraforaminal L5-S1 LDH were included in this study. All patients underwent TLED, being subsequently evaluated in a 2-year follow-up period. Assessment was performed preoperatively and at 6 weeks and 3, 6, 12 and 24 months postoperatively. Visual Analogue Scale (distinctly applied for lower limb - VAS-LP and low back - VAS-BP pain) and Short-Form 36 (SF-36) Medical Health Survey Questionnaire were implemented to assess pain and health-related quality of life (HRQoL) of enrolled individuals, respectively.
UNASSIGNED: No major perioperative complications were observed. Recorded values of all studied indices were demonstrated to feature a clinically and statistically significant amelioration at 6 weeks, presenting lesser improvement at 3 months with subsequent stabilisation. VAS-LP and VAS-BP values were displayed to reach a plateau in 6 months postoperatively, whereas all parameters of SF-36 continued to present a statistically significant improvement until the end of follow-up at 2 years.
UNASSIGNED: TLED represent a safe and efficient technique in terms of diminishing perceived pain and improving HRQoL in patients with L5-S1 LDHs. However, specific patient- and technique-related circumstances on the ground of low surgical experience may limit its effectiveness in these patients.
摘要：
■这项研究的目的是探讨L5-S1腰椎间盘突出症（LDH）患者的经椎间孔镜椎间盘切除术（TLED）的临床疗效。
■本研究包括75例连续诊断为椎间孔/椎间孔外L5-S1LDH的个体。所有患者都接受了TLED，随后在2年的随访期内进行评估。评估在术前和术后6周以及术后3、6、12和24个月进行。采用视觉模拟量表(明显适用于下肢-VAS-LP和下背部-VAS-BP疼痛)和简表36(SF-36)医疗健康调查问卷,评估入选个体的疼痛和健康相关生活质量(HRQoL),分别。
■未观察到重大围手术期并发症。所有研究指标的记录值被证明在6周时具有临床和统计学上的显着改善，在3个月时表现出较小的改善，随后稳定下来。显示VAS-LP和VAS-BP值在术后6个月达到平台期,而SF-36的所有参数在2年随访结束前持续有统计学意义的改善.
■TLED在减少L5-S1LDHs患者的感知疼痛和改善HRQoL方面代表了一种安全有效的技术。然而,基于低手术经验的特定患者和技术相关情况可能会限制其在这些患者中的有效性.
■本研究包括75例连续诊断为椎间孔/椎间孔外L5-S1LDH的个体。所有患者都接受了TLED，随后在2年的随访期内进行评估。评估在术前和术后6周以及术后3、6、12和24个月进行。采用视觉模拟量表(明显适用于下肢-VAS-LP和下背部-VAS-BP疼痛)和简表36(SF-36)医疗健康调查问卷,评估入选个体的疼痛和健康相关生活质量(HRQoL),分别。
■未观察到重大围手术期并发症。所有研究指标的记录值被证明在6周时具有临床和统计学上的显着改善，在3个月时表现出较小的改善，随后稳定下来。显示VAS-LP和VAS-BP值在术后6个月达到平台期,而SF-36的所有参数在2年随访结束前持续有统计学意义的改善.
■TLED在减少L5-S1LDHs患者的感知疼痛和改善HRQoL方面代表了一种安全有效的技术。然而,基于低手术经验的特定患者和技术相关情况可能会限制其在这些患者中的有效性.
