PDF(Pubmed)
Abstract：
OBJECTIVE: Our current study aimed to investigate the determinants of dementia among the oldest old using longitudinal data from a representative sample covering both community-dwelling and institutionalized individuals.
METHODS: Longitudinal representative data were taken from the \"Survey on quality of life and subjective well-being of the very old in North Rhine-Westphalia (NRW80+)\" that surveyed community-dwelling and institutionalized individuals aged 80 years and above (n = 1,296 observations in the analytic sample), living in North Rhine-Westphalia (most populous state of Germany). The established DemTect was used to measure cognitive impairment (i.e., probable dementia). A logistic random effects model was used to examine the determinants of probable dementia.
RESULTS: The mean age was 86.3 years (SD: 4.2 years). Multiple logistic regressions revealed that a higher likelihood of probable dementia was positively associated with lower education (e.g., low education compared to medium education: OR: 3.31 [95% CI: 1.10-9.98]), a smaller network size (OR: 0.87 [95% CI: 0.79-0.96]), lower health literacy (OR: 0.29 [95% CI: 0.14-0.60]), and higher functional impairment (OR: 13.45 [3.86-46.92]), whereas it was not significantly associated with sex, age, marital status, loneliness, and depressive symptoms in the total sample. Regressions stratified by sex were also reported.
CONCLUSIONS: Our study identified factors associated with dementia among the oldest old. This study extends current knowledge by using data from the oldest old; and by presenting findings based on longitudinal, representative data (also including individuals residing in institutionalized settings).
CONCLUSIONS: Efforts to increase, among other things, formal education, network size, and health literacy may be fruitful in postponing dementia, particularly among older women. Developing health literacy programs, for example, may be beneficial to reduce the burden associated with dementia.
METHODS: Longitudinal representative data were taken from the \"Survey on quality of life and subjective well-being of the very old in North Rhine-Westphalia (NRW80+)\" that surveyed community-dwelling and institutionalized individuals aged 80 years and above (n = 1,296 observations in the analytic sample), living in North Rhine-Westphalia (most populous state of Germany). The established DemTect was used to measure cognitive impairment (i.e., probable dementia). A logistic random effects model was used to examine the determinants of probable dementia.
RESULTS: The mean age was 86.3 years (SD: 4.2 years). Multiple logistic regressions revealed that a higher likelihood of probable dementia was positively associated with lower education (e.g., low education compared to medium education: OR: 3.31 [95% CI: 1.10-9.98]), a smaller network size (OR: 0.87 [95% CI: 0.79-0.96]), lower health literacy (OR: 0.29 [95% CI: 0.14-0.60]), and higher functional impairment (OR: 13.45 [3.86-46.92]), whereas it was not significantly associated with sex, age, marital status, loneliness, and depressive symptoms in the total sample. Regressions stratified by sex were also reported.
CONCLUSIONS: Our study identified factors associated with dementia among the oldest old. This study extends current knowledge by using data from the oldest old; and by presenting findings based on longitudinal, representative data (also including individuals residing in institutionalized settings).
CONCLUSIONS: Efforts to increase, among other things, formal education, network size, and health literacy may be fruitful in postponing dementia, particularly among older women. Developing health literacy programs, for example, may be beneficial to reduce the burden associated with dementia.
摘要：
目的：我们目前的研究旨在使用来自社区居住和住院个体的代表性样本的纵向数据来调查年龄最大的老年人痴呆的决定因素。
方法：纵向代表性数据取自“北莱茵-威斯特法伦州老年人（NRW80）的生活质量和主观幸福感调查”，该调查调查了80岁及以上的社区居住和机构化个人（分析样本中n=1,296个观察值），生活在北莱茵-威斯特法伦州（德国人口最多的州）。建立的DemTect用于测量认知障碍(即，可能的痴呆症）。使用逻辑随机效应模型来检查可能的痴呆的决定因素。
结果：平均年龄为86.3岁（SD：4.2岁）。多重逻辑回归显示，可能的痴呆的可能性较高与受教育程度较低呈正相关(例如，与中等教育相比，教育程度较低：OR：3.31[95%CI：1.10-9.98])，较小的网络大小(OR：0.87[95%CI：0.79-0.96])，健康素养较低(OR：0.29[95%CI：0.14-0.60])，和更高的功能损害(OR：13.45[3.86-46.92])，虽然它与性别没有显著关系，年龄,婚姻状况,孤独,总样本中的抑郁症状。还报告了按性别分层的回归。
结论：我们的研究确定了与年龄最大的老年人痴呆相关的因素。这项研究通过使用来自最古老的老年人的数据来扩展当前的知识；并通过基于纵向，代表性数据(也包括居住在制度化环境中的个人)。
结论：努力增加，除其他外，正规教育,网络大小，健康素养在延缓痴呆症方面可能会有成效，尤其是老年妇女。制定健康素养计划，例如,可能有利于减轻与痴呆相关的负担。
方法：纵向代表性数据取自“北莱茵-威斯特法伦州老年人（NRW80）的生活质量和主观幸福感调查”，该调查调查了80岁及以上的社区居住和机构化个人（分析样本中n=1,296个观察值），生活在北莱茵-威斯特法伦州（德国人口最多的州）。建立的DemTect用于测量认知障碍(即，可能的痴呆症）。使用逻辑随机效应模型来检查可能的痴呆的决定因素。
结果：平均年龄为86.3岁（SD：4.2岁）。多重逻辑回归显示，可能的痴呆的可能性较高与受教育程度较低呈正相关(例如，与中等教育相比，教育程度较低：OR：3.31[95%CI：1.10-9.98])，较小的网络大小(OR：0.87[95%CI：0.79-0.96])，健康素养较低(OR：0.29[95%CI：0.14-0.60])，和更高的功能损害(OR：13.45[3.86-46.92])，虽然它与性别没有显著关系，年龄,婚姻状况,孤独,总样本中的抑郁症状。还报告了按性别分层的回归。
结论：我们的研究确定了与年龄最大的老年人痴呆相关的因素。这项研究通过使用来自最古老的老年人的数据来扩展当前的知识；并通过基于纵向，代表性数据(也包括居住在制度化环境中的个人)。
结论：努力增加，除其他外，正规教育,网络大小，健康素养在延缓痴呆症方面可能会有成效，尤其是老年妇女。制定健康素养计划，例如,可能有利于减轻与痴呆相关的负担。
