Abstract：
Preoperative cytopathology of pancreatobiliary neoplastic lesions is a sensitive and specific method and is irreplaceable in the diagnosis and clinical management of these diseases. Pathologists should make every attempt to provide diagnosis as precise as possible and minimize the rate of \"atypical\" results, which create management dilemmas. The diagnostic accuracy of cytopathology can be significantly improved by judicious use of ancillary studies, including immunohistochemistry and molecular genetics. Next generation sequencing (NGS) is the latest addition to pancreatobiliary cytopathology diagnostic arsenal. NGS is not only a very robust diagnostic tool, but also carries significant prognostic and therapeutic information.
摘要：
胰胆管肿瘤病变的术前细胞病理学检查是一种敏感而特异的方法，在这些疾病的诊断和临床治疗中是不可替代的。病理学家应尽一切努力提供尽可能精确的诊断，并尽量减少“非典型”结果的发生率，造成管理困境。通过明智地使用辅助研究，可以显着提高细胞病理学的诊断准确性。包括免疫组织化学和分子遗传学。下一代测序（NGS）是胰胆管细胞病理学诊断库的最新补充。NGS不仅是一个非常强大的诊断工具，但也携带重要的预后和治疗信息。
