Abstract：
The Australian Scleroderma Interest Group (ASIG) algorithm for screening pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc) requires only respiratory function tests and serum N-terminal pro-brain natriuretic peptide as first-tier tests, and is recommended in international guidelines. In this communication, we present the findings of the application of the ASIG screening algorithm to a Singaporean cohort undergoing prospective annual screening for PAH, which shows a high negative predictive value. The ASIG algorithm may offer an alternative to more complex and costly SSc-PAH screening algorithms.
摘要：
用于筛查系统性硬化症（SSc）中肺动脉高压（PAH）的澳大利亚硬皮病兴趣小组（ASIG）算法仅需要进行呼吸功能检查和血清N末端脑钠肽前体作为一级测试，并在国际准则中被推荐。在这份通讯中,我们介绍了将ASIG筛查算法应用于正在进行PAH前瞻性年度筛查的新加坡队列的结果，显示出较高的阴性预测值。ASIG算法可以提供更复杂和昂贵的SSc-PAH筛选算法的替代方案。
