PDF(Pubmed)
Abstract：
The objective were to evaluate the effects of supplementation of standardized dry extract of Rosmarinus officinalis (RO) and the application of aesthetic radiofrequency on the oxidative stress markers catalase (CAT), superoxide dismutase (SOD), non-protein thiols (NP-SH), and thiobarbituric acid reactive species (TBARS) and the biochemical markers triglycerides, total cholesterol, high density lipoprotein (HDL) cholesterol, glutamic-oxaloacetic transaminase (TGO/AST), pyruvic-glutamic transaminase (TGP/ALT), gamma glutamyl transpeptidase (gamma-GT), and creatinine. This study included 32 women received the aesthetic therapy to reduce localized fat. They were divided into the control group (n = 8) receiving placebo capsules and the intervention group (n = 24) subdivided into Group A, B, and C, each with eight members receiving supplementation with 100, 500, and 1000 mg/day of standardized dry extract of RO, respectively. The Universal Trial Number (UTN) - U1111-1274-6255. Supplementation with RO (500 mg/day) demonstrated a reduction in oxidative stress (quantified with through a significant increase in NP-SH and a reduction in SOD and CAT enzymes). The radiofrequency aesthetic treatment did not promote an increase in oxidative stress; however, it caused significant changes in total cholesterol, HDL cholesterol, and creatinine. RO is a plant with antioxidant effects and its oral consumption is safe in selected women subjects in hepatic and renal markers.
摘要：
目的是评估添加迷迭香标准干提取物（RO）和美学射频对氧化应激标志物过氧化氢酶（CAT）的影响，超氧化物歧化酶（SOD），非蛋白质硫醇（NP-SH），和硫代巴比妥酸反应物质（TBARS）和生化标记甘油三酯，总胆固醇,高密度脂蛋白（HDL）胆固醇，谷氨酸-草酰乙酸转氨酶（TGO/AST），丙酮酸-谷氨酸转氨酶（TGP/ALT），γ-谷氨酰转肽酶(γ-GT),和肌酐。这项研究包括32名接受美容治疗以减少局部脂肪的女性。分为接受安慰剂胶囊的对照组（n=8）和干预组（n=24），再分为A组，B,C,每个有八个成员接受补充100、500和1000毫克/天的标准RO干提取物，分别。通用试验编号（UTN）-U1111-1274-6255。补充RO(500mg/天)表明氧化应激降低(通过NP-SH的显著增加和SOD和CAT酶的减少定量)。射频美容治疗并没有促进氧化应激的增加；然而，它引起了总胆固醇的显著变化，HDL胆固醇,和肌酐。RO是一种具有抗氧化作用的植物，在选定的女性受试者中，其口服食用在肝脏和肾脏标志物方面是安全的。
