PDF(Pubmed)
Abstract：
Stem cell therapy (SCT) is a promising solution for addressing health challenges in Africa, particularly non-communicable diseases (NCDs). With their regenerative potential, stem cells have the inherent capacity to differentiate into numerous cell types for tissue repair. Despite infrastructural, ethical, and legal challenges, SCT holds immense promise for managing chronic illnesses and deep-seated tissue injuries. The rising prevalence of NCDs in Africa highlights the need for innovative strategies and treatment options. SCT offers hope in combating conditions like burns, osteoarthritis, diabetes, Alzheimer\'s disease, stroke, heart failure and cancer, potentially reducing the burden of NCDs on the continent. Despite SCT\'s opportunities in Africa, there are significant obstacles. However, published research on SCT in Africa is scarce, but recent initiatives such as the Basic School on Neural Stem Cells (NSC) express interest in developing NSC research in Africa. SCT research in African regions, notably on neurogenesis, demonstrates a concentration on studying neurological processes in indigenous settings. While progress has been made in South Africa and Nigeria, issues such as brain drain and impediments to innovation remain. Clinical trials have investigated the efficacy of stem cell treatments, emphasising both potential benefits and limitations in implementing these therapies efficiently. Financing research, developing regulatory frameworks, and resolving affordability concerns are critical steps toward realizing the potential of stem cell treatment in Africa.
摘要：
干细胞疗法（SCT）是解决非洲健康挑战的有前途的解决方案。特别是非传染性疾病。凭借他们的再生潜力，干细胞具有分化成用于组织修复的多种细胞类型的固有能力。尽管基础设施,伦理,和法律挑战，SCT在管理慢性疾病和深层组织损伤方面具有巨大的希望。非洲非传染性疾病发病率不断上升，这凸显了创新战略和治疗选择的必要性。SCT为对抗烧伤等疾病提供了希望，骨关节炎,糖尿病,老年痴呆症,中风,心力衰竭和癌症,有可能减轻非洲非传染性疾病的负担。尽管SCT在非洲有机会，存在重大障碍。然而,在非洲发表的关于SCT的研究很少，但是最近的倡议，如神经干细胞基础学校（NSC）表达了在非洲发展NSC研究的兴趣。非洲区域的SCT研究，特别是在神经发生方面，展示了专注于研究土著环境中的神经过程。虽然南非和尼日利亚取得了进展，人才流失和创新障碍等问题依然存在。临床试验研究了干细胞治疗的疗效，强调有效实施这些疗法的潜在益处和局限性。融资研究，制定监管框架，解决可负担性问题是实现非洲干细胞治疗潜力的关键步骤。
