基于双 - 4 - 羟基香豆素骨架的新型 α - 葡萄糖苷酶抑制剂的设计: 合成,评估 ,和计算机研究。
关键词: 1,2,3-Triazole-N-Phenylacetamide Bis-4-Hydroxycoumarin Molecular docking α-Glucosidase
Mesh : Glycoside Hydrolase Inhibitors / pharmacology chemistry chemical synthesis Molecular Docking Simulation Structure-Activity Relationship alpha-Glucosidases / metabolism chemistry Drug Design 4-Hydroxycoumarins / chemistry pharmacology chemical synthesis Computer Simulation Catalytic Domain Molecular Dynamics Simulation
来 源:
DOI:10.1038/s41598-024-69592-0
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