PDF(Pubmed)
Abstract：
UNASSIGNED: Newborns and small infants are unable to cooperate actively during diagnostic procedures; therefore, sedation is often employee to maintain immobilization and obtain high-quality images. However, these procedures are often indicated in sick, vulnerable, or hemodynamically unstable neonates and young infants, which raises the associated risks of sedation. This study summarizes our 4-year of experience with safe and effective procedural sedation in this vulnerable population.
UNASSIGNED: This retrospective study analyzed data on neonates and young infants who underwent non-painful diagnostic procedures from December 2019 to November 2023. Patients were categorized into the neonate (aged≦ 28 days) and the young infant (29 days ≦ aged ≦ 90 days) groups.
UNASSIGNED: Non-pharmacological strategies, including sleeping naturally, swaddling/facilitated tucking, non-nutritive sucking, and skin-to-skin care, can achieve a success rate for sedation about 98.4%. In terms of pharmacological methods, our institution primarily utilizes chloral hydrate for procedural sedation in neonates and young infants undergoing non-painful diagnostic procedures. Midazolam serves as an alternative sedative. Chloral hydrate alone demonstrated a 92.5% success rate on the first attempt, compared to midazolam alone, with an 85.11% success rate. Neonates experienced a higher incidence of adverse events during sedation compared to young infants.
UNASSIGNED: This study reviews our 4-year experience with procedural sedation in neonates and young infants. Chloral hydrate demonstrated a high degree of safety and efficacy in this population. However, supervision by skilled medical personnel and extended observation is required. In our institution, the experience with midazolam is limited in this population, and further research is warranted to establish its safety and efficacy. Non-pharmacological strategies can achieve an acceptable rate of sedation success, which can be used based on patient\'s tolerance.
UNASSIGNED: This retrospective study analyzed data on neonates and young infants who underwent non-painful diagnostic procedures from December 2019 to November 2023. Patients were categorized into the neonate (aged≦ 28 days) and the young infant (29 days ≦ aged ≦ 90 days) groups.
UNASSIGNED: Non-pharmacological strategies, including sleeping naturally, swaddling/facilitated tucking, non-nutritive sucking, and skin-to-skin care, can achieve a success rate for sedation about 98.4%. In terms of pharmacological methods, our institution primarily utilizes chloral hydrate for procedural sedation in neonates and young infants undergoing non-painful diagnostic procedures. Midazolam serves as an alternative sedative. Chloral hydrate alone demonstrated a 92.5% success rate on the first attempt, compared to midazolam alone, with an 85.11% success rate. Neonates experienced a higher incidence of adverse events during sedation compared to young infants.
UNASSIGNED: This study reviews our 4-year experience with procedural sedation in neonates and young infants. Chloral hydrate demonstrated a high degree of safety and efficacy in this population. However, supervision by skilled medical personnel and extended observation is required. In our institution, the experience with midazolam is limited in this population, and further research is warranted to establish its safety and efficacy. Non-pharmacological strategies can achieve an acceptable rate of sedation success, which can be used based on patient\'s tolerance.
摘要：
■新生儿和小婴儿在诊断过程中无法积极合作；因此，镇静通常是员工保持固定和获得高质量的图像。然而,这些程序通常在生病时显示，脆弱的,或血流动力学不稳定的新生儿和幼儿，这增加了镇静的相关风险。这项研究总结了我们在该脆弱人群中安全有效的程序性镇静的4年经验。
■这项回顾性研究分析了从2019年12月至2023年11月接受非疼痛诊断程序的新生儿和幼儿的数据。将患者分为新生儿（年龄≤28天）和年轻婴儿（29天≤年龄≤90天）组。
■非药物策略，包括自然睡觉，包裹/便利的塞住，非营养性吸吮,和皮肤对皮肤的护理，镇静成功率约为98.4%。就药理学方法而言，我们的机构主要利用水合氯醛对接受非疼痛诊断程序的新生儿和年轻婴儿进行程序性镇静.咪达唑仑作为一种替代镇静剂。仅水合氯醛在第一次尝试时显示出92.5%的成功率，与单独的咪达唑仑相比，成功率为85.11%。新生儿在镇静过程中的不良事件发生率高于幼儿。
■本研究回顾了我们在新生儿和小婴儿中进行手术镇静的4年经验。水合氯醛在该人群中表现出高度的安全性和有效性。然而,需要熟练医务人员的监督和长期观察。在我们的机构里,使用咪达唑仑的经验在这个人群中是有限的，需要进一步研究以确定其安全性和有效性。非药物策略可以达到可接受的镇静成功率，可以根据患者的耐受性使用。
■这项回顾性研究分析了从2019年12月至2023年11月接受非疼痛诊断程序的新生儿和幼儿的数据。将患者分为新生儿（年龄≤28天）和年轻婴儿（29天≤年龄≤90天）组。
■非药物策略，包括自然睡觉，包裹/便利的塞住，非营养性吸吮,和皮肤对皮肤的护理，镇静成功率约为98.4%。就药理学方法而言，我们的机构主要利用水合氯醛对接受非疼痛诊断程序的新生儿和年轻婴儿进行程序性镇静.咪达唑仑作为一种替代镇静剂。仅水合氯醛在第一次尝试时显示出92.5%的成功率，与单独的咪达唑仑相比，成功率为85.11%。新生儿在镇静过程中的不良事件发生率高于幼儿。
■本研究回顾了我们在新生儿和小婴儿中进行手术镇静的4年经验。水合氯醛在该人群中表现出高度的安全性和有效性。然而,需要熟练医务人员的监督和长期观察。在我们的机构里,使用咪达唑仑的经验在这个人群中是有限的，需要进一步研究以确定其安全性和有效性。非药物策略可以达到可接受的镇静成功率，可以根据患者的耐受性使用。
