PDF(Pubmed)
Abstract：
UNASSIGNED: High blood pressure (BP) is a major risk factor for cardiovascular disease. The triglyceride-glucose (TyG) index is a useful tool for identifying insulin resistance at an early stage and has been proposed as a cost-effective predictor for hypertension. However, available studies are limited. This study aims to investigate the association between the TyG index and BP.
UNASSIGNED: Retrospective hospital data of a large cohort (n=1596) of adults aged ≥18 in Saudi Arabia were analyzed. The TyG index was calculated. Lipid markers, systolic BP (SBP), diastolic BP (DBP), and body mass index (BMI) were included.
UNASSIGNED: Across quartiles of the TyG index, SBP was significantly higher in those with higher vs lower TyG (p<0.03). No significant association was observed for DBP. A 2-SD higher SBP was significantly associated with a TyG difference of 1.7 (95% CI: 0.1, 3.3). In subgroup analysis, the relationship prevailed in females only [1.8 (95% CI: 0.3, 3.3)]. Across BMI categories (normal, overweight, obesity), the association between SBP and TyG was observed in participants with obesity only.
UNASSIGNED: The TyG index may act as a cost-effective predictive marker for high blood pressure, especially among specific subgroups. Future prospective studies are needed to confirm this relationship.
UNASSIGNED: Retrospective hospital data of a large cohort (n=1596) of adults aged ≥18 in Saudi Arabia were analyzed. The TyG index was calculated. Lipid markers, systolic BP (SBP), diastolic BP (DBP), and body mass index (BMI) were included.
UNASSIGNED: Across quartiles of the TyG index, SBP was significantly higher in those with higher vs lower TyG (p<0.03). No significant association was observed for DBP. A 2-SD higher SBP was significantly associated with a TyG difference of 1.7 (95% CI: 0.1, 3.3). In subgroup analysis, the relationship prevailed in females only [1.8 (95% CI: 0.3, 3.3)]. Across BMI categories (normal, overweight, obesity), the association between SBP and TyG was observed in participants with obesity only.
UNASSIGNED: The TyG index may act as a cost-effective predictive marker for high blood pressure, especially among specific subgroups. Future prospective studies are needed to confirm this relationship.
摘要：
■高血压（BP）是心血管疾病的主要危险因素。甘油三酯-葡萄糖（TyG）指数是早期识别胰岛素抵抗的有用工具，并已被提出作为高血压的经济有效预测指标。然而,现有的研究是有限的。本研究旨在探讨TyG指数与BP之间的关系。
■分析了沙特阿拉伯18岁以上成年人的大型队列（n=1596）的回顾性医院数据。计算TyG指数。脂质标记,收缩压血压（SBP），舒张压血压（DBP），包括体重指数（BMI）。
■跨TyG指数的四分位数，TyG较高的患者SBP明显高于TyG较低的患者(p<0.03)。未观察到DBP的显著关联。2-SD较高的SBP与1.7的TyG差异显着相关（95％CI：0.1，3.3）。在亚组分析中，这种关系仅在女性中盛行[1.8(95%CI:0.3,3.3)]。跨BMI类别（正常，超重,肥胖)，仅在肥胖参与者中观察到SBP和TyG之间的关联.
■TyG指数可能是高血压的具有成本效益的预测指标，尤其是在特定的亚组中。需要未来的前瞻性研究来证实这种关系。
■分析了沙特阿拉伯18岁以上成年人的大型队列（n=1596）的回顾性医院数据。计算TyG指数。脂质标记,收缩压血压（SBP），舒张压血压（DBP），包括体重指数（BMI）。
■跨TyG指数的四分位数，TyG较高的患者SBP明显高于TyG较低的患者(p<0.03)。未观察到DBP的显著关联。2-SD较高的SBP与1.7的TyG差异显着相关（95％CI：0.1，3.3）。在亚组分析中，这种关系仅在女性中盛行[1.8(95%CI:0.3,3.3)]。跨BMI类别（正常，超重,肥胖)，仅在肥胖参与者中观察到SBP和TyG之间的关联.
■TyG指数可能是高血压的具有成本效益的预测指标，尤其是在特定的亚组中。需要未来的前瞻性研究来证实这种关系。
