{Reference Type}: Journal Article
{Title}: Triglyceride-Glucose Index (TyG Index) in Association with Blood Pressure in Adults: A Retrospective Study.
{Author}: Aljuraiban GS;Alharbi FJ;Aljohi AO;Almeshari AZ;Al-Musharraf SI;Aldhwayan MM;Alshaikh F;Abulmeaty M;
{Journal}: Int J Gen Med
{Volume}: 17
{Issue}: 0
{Year}: 2024
{Factor}: 2.145
{DOI}: 10.2147/IJGM.S469147
{Abstract}: <B>UNASSIGNED: </B>High blood pressure (BP) is a major risk factor for cardiovascular disease. The triglyceride-glucose (TyG) index is a useful tool for identifying insulin resistance at an early stage and has been proposed as a cost-effective predictor for hypertension. However, available studies are limited. This study aims to investigate the association between the TyG index and BP.<BR><B>UNASSIGNED: </B>Retrospective hospital data of a large cohort (n=1596) of adults aged ≥18 in Saudi Arabia were analyzed. The TyG index was calculated. Lipid markers, systolic BP (SBP), diastolic BP (DBP), and body mass index (BMI) were included.<BR><B>UNASSIGNED: </B>Across quartiles of the TyG index, SBP was significantly higher in those with higher vs lower TyG (p<0.03). No significant association was observed for DBP. A 2-SD higher SBP was significantly associated with a TyG difference of 1.7 (95% CI: 0.1, 3.3). In subgroup analysis, the relationship prevailed in females only [1.8 (95% CI: 0.3, 3.3)]. Across BMI categories (normal, overweight, obesity), the association between SBP and TyG was observed in participants with obesity only.<BR><B>UNASSIGNED: </B>The TyG index may act as a cost-effective predictive marker for high blood pressure, especially among specific subgroups. Future prospective studies are needed to confirm this relationship.