PDF(Pubmed)
Abstract：
UNASSIGNED: Stiff person syndrome (SPS) is a rare autoimmune disorder that affects the central nervous system. Patients with this condition may experience sudden muscle spasms, leading to falls and subsequent fractures. Diagnosis is based on clinical presentation, the presence of anti-GAD antibodies, and electromyography (EMG) findings that show continuous motor unit activity. However, there have been few reports of atraumatic fractures in these patients.
METHODS: In this article, we present a case of a patient with stiff person syndrome who sustained an intertrochanteric fracture without any prior history of trauma. Additionally, we review and discuss previous literature on this subject.
UNASSIGNED: SPS is a rare autoimmune neurological disease with muscle rigidity and spasms predominantly in the trunk and lower limbs. The authors mentioned that SPS diagnosis and managing related fractures could be challenging. They recommended optimizing the patient\'s status with proper medical treatments before surgical interventions to reduce further complications.
CONCLUSIONS: In conclusion, it appears that stiff person syndrome can lead to recurrent and even atraumatic fractures, and should be considered as an underlying cause. Additionally, uncontrolled spasms in these patients can result in the failure of previous surgical fixations and complicated surgical management. To prevent surgical complications, it is crucial to initiate and maintain appropriate medical treatment to control spasms as soon as the underlying disease is diagnosed.
METHODS: In this article, we present a case of a patient with stiff person syndrome who sustained an intertrochanteric fracture without any prior history of trauma. Additionally, we review and discuss previous literature on this subject.
UNASSIGNED: SPS is a rare autoimmune neurological disease with muscle rigidity and spasms predominantly in the trunk and lower limbs. The authors mentioned that SPS diagnosis and managing related fractures could be challenging. They recommended optimizing the patient\'s status with proper medical treatments before surgical interventions to reduce further complications.
CONCLUSIONS: In conclusion, it appears that stiff person syndrome can lead to recurrent and even atraumatic fractures, and should be considered as an underlying cause. Additionally, uncontrolled spasms in these patients can result in the failure of previous surgical fixations and complicated surgical management. To prevent surgical complications, it is crucial to initiate and maintain appropriate medical treatment to control spasms as soon as the underlying disease is diagnosed.
摘要：
■硬人综合征（SPS）是一种罕见的自身免疫性疾病，会影响中枢神经系统。有这种情况的患者可能会出现突然的肌肉痉挛，导致跌倒和随后的骨折。诊断基于临床表现，抗GAD抗体的存在，和肌电图（EMG）发现显示连续的运动单位活动。然而,这些患者中很少有无创伤骨折的报道。
方法：在本文中，我们介绍了一例患有僵硬人综合征的患者，该患者患有股骨转子间骨折，没有任何创伤史。此外,我们回顾和讨论以前关于这个主题的文献。
■SPS是一种罕见的自身免疫性神经系统疾病，主要在躯干和下肢出现肌肉僵硬和痉挛。作者提到，SPS诊断和处理相关骨折可能具有挑战性。他们建议在手术干预之前通过适当的药物治疗来优化患者的状态，以减少进一步的并发症。
结论：结论：看起来僵硬的人综合征可能会导致复发性骨折，甚至是无创伤骨折，应该被认为是一个根本原因。此外,这些患者不受控制的痉挛可能导致先前手术固定的失败和复杂的手术管理。为了防止手术并发症，一旦诊断出潜在疾病，开始并维持适当的药物治疗以控制痉挛至关重要。
方法：在本文中，我们介绍了一例患有僵硬人综合征的患者，该患者患有股骨转子间骨折，没有任何创伤史。此外,我们回顾和讨论以前关于这个主题的文献。
■SPS是一种罕见的自身免疫性神经系统疾病，主要在躯干和下肢出现肌肉僵硬和痉挛。作者提到，SPS诊断和处理相关骨折可能具有挑战性。他们建议在手术干预之前通过适当的药物治疗来优化患者的状态，以减少进一步的并发症。
结论：结论：看起来僵硬的人综合征可能会导致复发性骨折，甚至是无创伤骨折，应该被认为是一个根本原因。此外,这些患者不受控制的痉挛可能导致先前手术固定的失败和复杂的手术管理。为了防止手术并发症，一旦诊断出潜在疾病，开始并维持适当的药物治疗以控制痉挛至关重要。
