PDF(Pubmed)
Abstract：
UNASSIGNED: We aimed to investigate the clinical findings of hospitalized paediatric COVID-19 patients by the end of 2022.
UNASSIGNED: All confirmed children with COVID-19 infection admitted into Chaozhou Central Hospital during the COVID-19 outbreak from 19 December 2022 to 1 February 2023 were included. Detailed clinical data of those children were evaluated retrospectively.
UNASSIGNED: A total of 286 children, ranging in age from 1 month to 13 years old, were diagnosed with SARS-CoV-2 infection. Among these cases, 138 (48.3%) were categorized as mild, 126 (44.0%) as moderate and 22 (7.7%) as severe/critical. Symptoms varied among the children and included fever, upper respiratory tract symptoms, convulsions, sore throat, poor appetite, dyspnoea and gastrointestinal symptoms. Notably, febrile convulsions were observed in 96 (33.6%) patients, while acute laryngitis was documented in 50 (17.5%) cases. Among the severe/critical patients, eight developed multisystem inflammatory syndrome in children (MIS-C), and tragically, one patient\'s condition worsened and resulted in death. Furthermore, MRI scans revealed abnormal brain signals in six severe/critical patients. The severe/critical group also exhibited more pronounced laboratory abnormalities, including decreased haemoglobin and elevated ALT, AST, LDH and CK levels.
UNASSIGNED: Febrile convulsions and acute laryngitis are frequently observed in children diagnosed with SARS-CoV-2 Omicron infection. Moreover, MIS-C and abnormal neuroimaging appear to be relatively common phenomena in severe/critical cases.
UNASSIGNED: All confirmed children with COVID-19 infection admitted into Chaozhou Central Hospital during the COVID-19 outbreak from 19 December 2022 to 1 February 2023 were included. Detailed clinical data of those children were evaluated retrospectively.
UNASSIGNED: A total of 286 children, ranging in age from 1 month to 13 years old, were diagnosed with SARS-CoV-2 infection. Among these cases, 138 (48.3%) were categorized as mild, 126 (44.0%) as moderate and 22 (7.7%) as severe/critical. Symptoms varied among the children and included fever, upper respiratory tract symptoms, convulsions, sore throat, poor appetite, dyspnoea and gastrointestinal symptoms. Notably, febrile convulsions were observed in 96 (33.6%) patients, while acute laryngitis was documented in 50 (17.5%) cases. Among the severe/critical patients, eight developed multisystem inflammatory syndrome in children (MIS-C), and tragically, one patient\'s condition worsened and resulted in death. Furthermore, MRI scans revealed abnormal brain signals in six severe/critical patients. The severe/critical group also exhibited more pronounced laboratory abnormalities, including decreased haemoglobin and elevated ALT, AST, LDH and CK levels.
UNASSIGNED: Febrile convulsions and acute laryngitis are frequently observed in children diagnosed with SARS-CoV-2 Omicron infection. Moreover, MIS-C and abnormal neuroimaging appear to be relatively common phenomena in severe/critical cases.
摘要：
■我们的目标是到2022年底调查住院儿科COVID-19患者的临床表现。
在2022年12月19日至2023年2月1日COVID-19爆发期间入住潮州市中心医院的所有确诊的COVID-19感染儿童均包括在内。回顾性评估了这些儿童的详细临床资料。
■总共286名儿童，年龄从1个月到13岁不等，被诊断为SARS-CoV-2感染。在这些案例中,138（48.3%）被归类为轻度，126（44.0％）为中度，22（7.7％）为严重/危急。儿童的症状各不相同，包括发烧，上呼吸道症状,抽搐,喉咙痛,食欲不振,呼吸困难和胃肠道症状。值得注意的是,在96例（33.6％）患者中观察到高热惊厥，在50例（17.5％）中记录了急性喉炎。在重症/危重症患者中，八例儿童多系统炎症综合征（MIS-C），可悲的是，一名患者的病情恶化并导致死亡。此外，MRI扫描显示6名重症/危重症患者的脑信号异常。严重/危重组也表现出更明显的实验室异常，包括血红蛋白下降和ALT升高，AST,LDH和CK水平。
■在被诊断为SARS-CoV-2Omicron感染的儿童中经常观察到高热惊厥和急性喉炎。此外，在严重/危重病例中，MIS-C和异常神经影像学似乎是相对常见的现象。
在2022年12月19日至2023年2月1日COVID-19爆发期间入住潮州市中心医院的所有确诊的COVID-19感染儿童均包括在内。回顾性评估了这些儿童的详细临床资料。
■总共286名儿童，年龄从1个月到13岁不等，被诊断为SARS-CoV-2感染。在这些案例中,138（48.3%）被归类为轻度，126（44.0％）为中度，22（7.7％）为严重/危急。儿童的症状各不相同，包括发烧，上呼吸道症状,抽搐,喉咙痛,食欲不振,呼吸困难和胃肠道症状。值得注意的是,在96例（33.6％）患者中观察到高热惊厥，在50例（17.5％）中记录了急性喉炎。在重症/危重症患者中，八例儿童多系统炎症综合征（MIS-C），可悲的是，一名患者的病情恶化并导致死亡。此外，MRI扫描显示6名重症/危重症患者的脑信号异常。严重/危重组也表现出更明显的实验室异常，包括血红蛋白下降和ALT升高，AST,LDH和CK水平。
■在被诊断为SARS-CoV-2Omicron感染的儿童中经常观察到高热惊厥和急性喉炎。此外，在严重/危重病例中，MIS-C和异常神经影像学似乎是相对常见的现象。
