UNASSIGNED: All confirmed children with COVID-19 infection admitted into Chaozhou Central Hospital during the COVID-19 outbreak from 19 December 2022 to 1 February 2023 were included. Detailed clinical data of those children were evaluated retrospectively.
UNASSIGNED: A total of 286 children, ranging in age from 1 month to 13 years old, were diagnosed with SARS-CoV-2 infection. Among these cases, 138 (48.3%) were categorized as mild, 126 (44.0%) as moderate and 22 (7.7%) as severe/critical. Symptoms varied among the children and included fever, upper respiratory tract symptoms, convulsions, sore throat, poor appetite, dyspnoea and gastrointestinal symptoms. Notably, febrile convulsions were observed in 96 (33.6%) patients, while acute laryngitis was documented in 50 (17.5%) cases. Among the severe/critical patients, eight developed multisystem inflammatory syndrome in children (MIS-C), and tragically, one patient\'s condition worsened and resulted in death. Furthermore, MRI scans revealed abnormal brain signals in six severe/critical patients. The severe/critical group also exhibited more pronounced laboratory abnormalities, including decreased haemoglobin and elevated ALT, AST, LDH and CK levels.
UNASSIGNED: Febrile convulsions and acute laryngitis are frequently observed in children diagnosed with SARS-CoV-2 Omicron infection. Moreover, MIS-C and abnormal neuroimaging appear to be relatively common phenomena in severe/critical cases.
在2022年12月19日至2023年2月1日COVID-19爆发期间入住潮州市中心医院的所有确诊的COVID-19感染儿童均包括在内。回顾性评估了这些儿童的详细临床资料。
■总共286名儿童,年龄从1个月到13岁不等,被诊断为SARS-CoV-2感染。在这些案例中,138(48.3%)被归类为轻度,126(44.0%)为中度,22(7.7%)为严重/危急。儿童的症状各不相同,包括发烧,上呼吸道症状,抽搐,喉咙痛,食欲不振,呼吸困难和胃肠道症状。值得注意的是,在96例(33.6%)患者中观察到高热惊厥,在50例(17.5%)中记录了急性喉炎。在重症/危重症患者中,八例儿童多系统炎症综合征(MIS-C),可悲的是,一名患者的病情恶化并导致死亡。此外,MRI扫描显示6名重症/危重症患者的脑信号异常。严重/危重组也表现出更明显的实验室异常,包括血红蛋白下降和ALT升高,AST,LDH和CK水平。
■在被诊断为SARS-CoV-2Omicron感染的儿童中经常观察到高热惊厥和急性喉炎。此外,在严重/危重病例中,MIS-C和异常神经影像学似乎是相对常见的现象。