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Abstract：
The aim of the present study was to assess the short-term behavioral and physiological responses of piglets to different treatment protocols for the control of iron-deficiency anemia (IDA) and cystoisosporosis. Piglets were treated with either (1) an injection of iron combined with an oral application of toltrazuril (TLZ) by drenching or (2) a combination injection of TZL + gleptoferron; the behavior of the piglets was then evaluated. For this study, 288 piglets were divided into three experimental groups: 96 piglets were kept untreated (control group); 96 piglets received an oral administration of a generic TZL-based anticoccidial agent (20 mg/kg BW) along with intramuscular administration of iron dextran (200 mg/mL; 1 mL/piglet) at the same handling (oral + parenteral group, O + P); and 96 piglets received an intramuscular application of the combination product (parenteral group, P). For each treated piglet, the total handling time, flight reaction, and the intensity and frequency of vocalizations were determined using the methodology described by Scollo et al. (2020). Piglets in the O + P group were found to emit more screams during treatment administration than animals in the P group (21.05% vs. 8.42% of animals; p < 0.05). Piglets in the O + P group reacted worse to manipulation and oral administration because a higher percentage of animals continued to fidget even after handling (32.63% vs. 12.63%; p < 0.05). Differences in growth performance between the groups were not observed in our study (p > 0.05). In conclusion, the administration of a combination product reduced stress during administration, as indicated by reduced vocalizations and reactions to manipulation.
摘要：
本研究的目的是评估仔猪对不同治疗方案的短期行为和生理反应，以控制缺铁性贫血（IDA）和囊孢子虫病。用（1）注射铁并通过滴注口服托曲唑（TLZ）或（2）注射TZLgleptoferron的组合治疗仔猪；然后评估仔猪的行为。对于这项研究，将288只仔猪分为三个实验组：96只仔猪未经处理（对照组）；96只仔猪在相同的处理下口服基于TZL的通用抗球虫药（20mg/kgBW）以及肌内施用右旋糖酐铁（200mg/mL；1mL/仔猪）（口服肠胃外组，O+P）；96只仔猪接受了组合产品的肌内施用（肠胃外组，P).对于每只处理过的仔猪，总处理时间，飞行反应,使用Scollo等人描述的方法确定发声的强度和频率。（2020年）。发现OP组的仔猪在治疗期间比P组的动物发出更多的尖叫声（21.05％vs.8.42%的动物；p<0.05）。OP组的仔猪对操作和口服给药的反应较差，因为即使在处理后，仍有较高比例的动物继续烦躁不安（32.63％vs.12.63%；p<0.05）。在我们的研究中没有观察到各组之间生长性能的差异(p>0.05)。总之,组合产品的给药减少了给药期间的压力，如减少的发声和对操纵的反应所表明的。
