关键词: cancer computed tomography malnutrition myosteatosis sarcopenia

来  源:   DOI:10.3390/cancers16152738   PDF(Pubmed)

Abstract:
The increase in the global incidence of cancer highlights the need to continue advancing in the techniques of diagnosis and nutritional assessment of cancer patients, given the prognostic and therapeutic impact of nutritional status. In this study, sarcopenia was evaluated as an independent predictor of morbidity and mortality. Data from 45 patients diagnosed with esophagogastric or pancreatic cancer were analyzed. Body composition was determined using computed tomography images, and functionality tests were performed. Sarcopenia was present in 22.2% of the patients, while only 31.1% had correct musculature. A reduction in muscle mass or function was observed in 46.7% of the patients. Likewise, the prevalence of myosteatosis reached 60% of the patients. No significant differences were found with regard to the presence of sarcopenia according to BMI classifications, so it is necessary to evaluate the patient with body composition techniques that include the evaluation of the different muscle and fat compartments. In conclusion, a comprehensive intervention is necessary to improve the detection of sarcopenia/myosteatosis and, in the future, to be able to carry out an approach that improves the quality of life and survival rates of patients.
摘要:
全球癌症发病率的增加凸显了在癌症患者的诊断和营养评估技术上继续进步的必要性。考虑到营养状况对预后和治疗的影响。在这项研究中,肌少症被评估为发病率和死亡率的独立预测因子.分析了45例诊断为食管胃癌或胰腺癌的患者的数据。使用计算机断层扫描图像确定身体成分,并进行了功能测试。22.2%的患者存在肌肉减少症,而只有31.1%的肌肉组织正确。在46.7%的患者中观察到肌肉质量或功能减少。同样,肌肉骨化病的患病率达到60%。根据BMI分类,关于肌少症的存在没有发现显着差异,因此,有必要用身体成分技术评估患者,包括评估不同的肌肉和脂肪区。总之,全面的干预是必要的,以提高肌肉减少症/肌萎缩症的检测,在未来,能够开展提高患者生活质量和生存率的方法。
公众号