Abstract：
Neonatal capillary leak syndrome (CLS) is a rare, but life-threatening condition following neonatal sepsis or inflammatory injury. The objective of this study was to describe a standardized treatment approach for CLS that improves mortality and neonatal outcomes. A retrospective cohort study of 10 infants born at 22 to 26 weeks of gestation who developed CLS following a significant inflammatory insult was performed. Time to diagnosis and treatment approaches over 2 epochs were recorded and described. In epoch 2, with increased clinical awareness of CLS and implementation of a standardized treatment approach, there was a non-statistically significant decrease in the time to treatment with a significant decrease in mortality. An early targeted treatment approach for neonatal CLS can decrease mortality rates in this highly morbid condition.
摘要：
新生儿毛细血管渗漏综合征(CLS)是一种罕见的,而是在新生儿败血症或炎性损伤后危及生命。这项研究的目的是描述一种改善死亡率和新生儿结局的CLS标准化治疗方法。对10名在妊娠22至26周出生的婴儿进行了回顾性队列研究，这些婴儿在明显的炎症损伤后发生了CLS。记录并描述了超过2个时期的诊断和治疗方法的时间。在时代2，随着临床对CLS认识的提高和标准化治疗方法的实施，治疗时间无统计学显著缩短,死亡率显著降低.新生儿CLS的早期靶向治疗方法可以降低这种高度病态的死亡率。
