推断单细胞中由 X 染色体失活状态指导的克隆体细胞突变。
关键词: Clonality Hematopoiesis Mutations X chromosome inactivation
Mesh : Humans X Chromosome Inactivation Female Mutation Single-Cell Analysis Leukocytes, Mononuclear / metabolism Chromosomes, Human, X / genetics Clone Cells T-Lymphocytes / metabolism Male DNA, Mitochondrial / genetics
来 源:
DOI:10.1186/s13059-024-03360-1
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