PDF(Pubmed)
Abstract：
OBJECTIVE: This umbrella review synthesises evidence on the methods used to recruit and retain ethnically diverse participants and report and analyse variables related to ethnic diversity in randomised controlled trials.
METHODS: Umbrella review.
METHODS: Ovid MEDLINE, Ovid Embase, CINAHL, PsycINFO and Cochrane and Campbell Libraries for review papers published between 1 January 2010 and 13 May 2024.
METHODS: English language systematic reviews focusing on inclusion and reporting of ethnicity variables. Methodological quality was assessed using the AMSTAR 2 tool.
RESULTS: Sixty-two systematic reviews were included. Findings point to limited representation and reporting of ethnic diversity in trials. Recruitment strategies commonly reported by the reviews were community engagement, advertisement, face-to-face recruitment, cultural targeting, clinical referral, community presentation, use of technology, incentives and research partnership with communities. Retention strategies highlighted by the reviews included frequent follow-ups on participants to check how they are doing in the study, provision of incentives, use of tailored approaches and culturally appropriate interventions. The findings point to a limited focus on the analysis of variables relevant to ethnic diversity in trials even when they are reported in trials.
CONCLUSIONS: Significant improvements are required in enhancing the recruitment and retention of ethnically diverse participants in trials as well as analysis and reporting of variables relating to diversity in clinical trials.
UNASSIGNED: CRD42022325241.
METHODS: Umbrella review.
METHODS: Ovid MEDLINE, Ovid Embase, CINAHL, PsycINFO and Cochrane and Campbell Libraries for review papers published between 1 January 2010 and 13 May 2024.
METHODS: English language systematic reviews focusing on inclusion and reporting of ethnicity variables. Methodological quality was assessed using the AMSTAR 2 tool.
RESULTS: Sixty-two systematic reviews were included. Findings point to limited representation and reporting of ethnic diversity in trials. Recruitment strategies commonly reported by the reviews were community engagement, advertisement, face-to-face recruitment, cultural targeting, clinical referral, community presentation, use of technology, incentives and research partnership with communities. Retention strategies highlighted by the reviews included frequent follow-ups on participants to check how they are doing in the study, provision of incentives, use of tailored approaches and culturally appropriate interventions. The findings point to a limited focus on the analysis of variables relevant to ethnic diversity in trials even when they are reported in trials.
CONCLUSIONS: Significant improvements are required in enhancing the recruitment and retention of ethnically diverse participants in trials as well as analysis and reporting of variables relating to diversity in clinical trials.
UNASSIGNED: CRD42022325241.
摘要：
目的：本综述综合了在随机对照试验中招募和留住种族多样性参与者的方法的证据，并报告和分析了与种族多样性相关的变量。
方法：雨伞综述。
方法：OvidMEDLINE，OvidEmbase,CINAHL,PsycINFO和Cochrane和Campbell图书馆在2010年1月1日至2024年5月13日之间发表的评论论文。
方法：英语系统评价侧重于种族变量的纳入和报告。使用AMSTAR2工具评估方法学质量。
结果：纳入62篇系统综述。研究结果表明，试验中种族多样性的代表性和报告有限。审查通常报告的招聘策略是社区参与，广告,面对面招募,文化定位,临床转诊,社区介绍,使用技术，激励措施和与社区的研究伙伴关系。评论强调的保留策略包括对参与者进行频繁的随访，以检查他们在研究中的表现。提供激励措施，使用量身定制的方法和文化上适当的干预措施。研究结果表明，即使在试验中报告了与试验中种族多样性相关的变量，对分析的关注也有限。
结论：在增加试验中种族多样性参与者的招募和保留以及在临床试验中与多样性相关的变量的分析和报告方面需要显著改进。
■CRD42022325241。
方法：雨伞综述。
方法：OvidMEDLINE，OvidEmbase,CINAHL,PsycINFO和Cochrane和Campbell图书馆在2010年1月1日至2024年5月13日之间发表的评论论文。
方法：英语系统评价侧重于种族变量的纳入和报告。使用AMSTAR2工具评估方法学质量。
结果：纳入62篇系统综述。研究结果表明，试验中种族多样性的代表性和报告有限。审查通常报告的招聘策略是社区参与，广告,面对面招募,文化定位,临床转诊,社区介绍,使用技术，激励措施和与社区的研究伙伴关系。评论强调的保留策略包括对参与者进行频繁的随访，以检查他们在研究中的表现。提供激励措施，使用量身定制的方法和文化上适当的干预措施。研究结果表明，即使在试验中报告了与试验中种族多样性相关的变量，对分析的关注也有限。
结论：在增加试验中种族多样性参与者的招募和保留以及在临床试验中与多样性相关的变量的分析和报告方面需要显著改进。
■CRD42022325241。
