Abstract：
The pre-fusion coronavirus HKU1 spike binds host sialoglycans and proteinaceous receptor TMPRSS2 for cell entry. In this issue of Cell, three papers by Fernández et al., McCallum et al., and Wang et al. provide structural information on HKU1 spike interactions with host receptors, providing insights into its multi-step opening.
摘要：
融合前冠状病毒HKU1刺突结合宿主唾液酸聚糖和蛋白质受体TMPRSS2以进入细胞。在本期《细胞》中,费尔南德斯等人的三篇论文。,McCallum等人。,和Wang等人。提供HKU1与宿主受体相互作用的结构信息，提供对其多步骤开放的见解。
