Abstract：
Herein, we present two cases of isolated suprasellar dissemination of glioblastoma in patients with well-controlled primary lesions. A 22-year-old woman and a 56-year-old woman developed rapid growth of suprasellar glioblastoma dissemination 26 and 17 months after initial surgery, respectively. Both patients presented with acute visual impairment (decreased acuity and visual field disturbances) but lacked severe pituitary dysfunction. During surgery for the disseminated tumors, gross total tumor resection was difficult due to intraoperative findings suggesting optic pathway invasion. Both patients developed further intracranial dissemination within several months post-surgery. The presence of solitary sellar and suprasellar dissemination may indicate a terminal stage.
摘要：
在这里，我们报告了2例原发性病变控制良好的胶质母细胞瘤孤立的鞍上播散病例。一名22岁的女性和一名56岁的女性在初次手术后26和17个月出现了快速生长的鞍上胶质母细胞瘤扩散，分别。两名患者均出现急性视力障碍（视力下降和视野障碍），但缺乏严重的垂体功能障碍。在播散性肿瘤的手术中，由于术中发现提示视路侵犯,因此难以切除整个肿瘤.两名患者在手术后几个月内进一步颅内扩散。孤立鞍和鞍上播散的存在可能表明晚期。
