Abstract:
To build a functional inner ear, hair cell morphology must be precisely controlled along the proximo-distal axis. A new paper in Development shows that differential mitochondrial dynamics in proximal versus distal cells impacts on the apical cell surface area - a key aspect of morphology. To find out more about this work, we spoke to first author James O\'Sullivan and senior author Zoë Mann, both at King\'s College London, UK.
摘要:
为了建立一个功能性的内耳,毛细胞形态必须沿着近端-远端轴精确控制。《发展》杂志的一篇新论文表明,近端和远端细胞的线粒体动力学差异会影响顶端细胞表面积-这是形态学的一个关键方面。为了了解更多关于这项工作的信息,我们采访了第一作者詹姆斯·奥沙利文和资深作者佐伊·曼,都在伦敦国王学院,英国。