关键词: Video-assisted thoracoscopic surgery (VATS) lung cancer open-source software three-dimensional reconstruction three-dimensional simulation

来  源:   DOI:10.21037/tlcr-24-134   PDF(Pubmed)

Abstract:
UNASSIGNED: Preoperative three-dimensional (3D) lung reconstructions can reduce intraoperative blood loss, conversion rate, and operation duration. These 3D reconstructions are predominantly provided by commercial expensive products, hence we aimed to assess the usability and performance of preoperative 3D lung reconstructions created with open-source software.
UNASSIGNED: Patients were invited to participate in this prospective pilot study if they were planned for uniportal video-assisted thoracoscopic surgery (VATS) lobectomy or segmentectomy between January and February 2023. Participants were excluded if a two-dimensional (2D) late-arterial-phase computed tomography (CT) scan contained motion artifacts, another surgical procedure was performed, or the surgery was canceled. After informed consent was obtained, 3D lung reconstructions were constructed using open-source 3D Slicer software. The system usability score (SUS) questionnaire assessed the usability of these reconstructions, whilst performance was evaluated based on anatomical validity compared to prior 2D CT assessment as well as operative findings. Descriptive statistics were reported.
UNASSIGNED: Thirteen patients were included, of whom one underwent a segmentectomy. Eighty-three percent of the 3D lung reconstructions scored above average (SUS >68). Compared to 2D CT scans, 38% of lung nodule segmental locations were detected more accurately through 3D lung reconstructions. Furthermore, 3D lung reconstructions revealed anatomical variations in 62%, which were not recognized on 2D CT scans, and provided surgeons with insights that would change the procedure and/or transection planes in 62%. One 3D lung reconstruction failed to demonstrate an intraoperative recognized segmental pulmonary artery (A6) branch.
UNASSIGNED: Three-dimensional lung reconstructions created with open-source software were usable and effective for uniportal VATS anatomical resections.
UNASSIGNED: ClinicalTrials.gov/NCT06132607.
摘要:
术前三维(3D)肺重建可减少术中失血,转化率,和操作持续时间。这些3D重建主要由商业昂贵的产品提供,因此,我们旨在评估使用开源软件创建的术前3D肺重建的可用性和性能.
如果计划在2023年1月至2月之间进行单孔视频胸腔镜手术(VATS)肺叶切除术或节段切除术,则邀请患者参加这项前瞻性试点研究。如果二维(2D)晚期动脉期计算机断层扫描(CT)扫描包含运动伪影,则排除参与者。进行了另一个外科手术,或者手术被取消了.在获得知情同意后,使用开源3D切片器软件构建3D肺重建。系统可用性得分(SUS)问卷评估了这些重建的可用性,同时,根据与先前的2DCT评估以及手术发现相比的解剖学有效性来评估性能。报告了描述性统计数据。
包括13名患者,其中一人接受了节段切除术。83%的3D肺重建得分高于平均水平(SUS>68)。与二维CT扫描相比,通过3D肺重建更准确地检测到38%的肺结节节段位置。此外,3D肺重建显示62%的解剖学变异,在二维CT扫描中无法识别,并为62%的外科医生提供了可以改变手术和/或横切平面的见解。一次3D肺重建未能证明术中识别的节段性肺动脉(A6)分支。
使用开源软件创建的三维肺重建可用于单通道VATS解剖切除。
临床试验.gov/NCT06132607。
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