关键词: dopamine agonists emerging therapies hormonal disorders individualized therapy pharmacological therapy prolactinoma surgical interventions

来  源:   DOI:10.1097/MS9.0000000000002308   PDF(Pubmed)

Abstract:
This narrative review provides a succinct exploration of prolactinoma, the most common pituitary adenoma, focusing on its epidemiology, clinical manifestations, and therapeutic interventions. Beginning with an overview of its prevalence and aetiology, the review delves into the gender distribution and familial associations of prolactinoma. Clinical presentations, including endocrine disruptions, reproductive health issues, and metabolic disturbances, are examined, emphasizing their impact on hormonal regulation and cardiovascular health. The narrative then navigates through pharmacological treatments, surgical interventions, and radiation therapy, highlighting their efficacy, side effects, and long-term management challenges. Strategies to mitigate side effects and optimize treatment outcomes are discussed, emphasizing the importance of multidisciplinary collaboration in prolactinoma management. This review is a concise yet comprehensive resource for healthcare professionals and researchers, providing insights into prolactinoma\'s clinical complexities and therapeutic nuances to guide optimal patient care strategies.
摘要:
这篇叙述性综述提供了对泌乳素瘤的简洁探索,最常见的垂体腺瘤,专注于其流行病学,临床表现,和治疗干预措施。从其患病率和病因的概述开始,本综述探讨了泌乳素腺瘤的性别分布和家族性关联.临床表现,包括内分泌干扰,生殖健康问题,和代谢紊乱,被检查,强调它们对荷尔蒙调节和心血管健康的影响。然后叙述通过药物治疗,手术干预,和放射治疗,突出它们的功效,副作用,和长期管理挑战。讨论了减轻副作用和优化治疗结果的策略,强调多学科合作在泌乳素瘤管理中的重要性。这篇综述是为医疗保健专业人员和研究人员提供的简明而全面的资源,提供对催乳素瘤的临床复杂性和治疗细微差别的见解,以指导最佳的患者护理策略。
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