UNASSIGNED: The purpose of this study is to identify geographic disparities in liver cancer by exploring the spatial and temporal trends of liver cancer mortality and the years of life lost (YLL) caused by it within distinct geographical regions, climate zones, and population groups in China.
UNASSIGNED: Data from the National Death Surveillance System between 2013 and 2020 were used to calculate the age-standardized mortality rate of liver cancer (LASMR) and YLL from liver cancer in China. The spatial distribution and temporal trends of liver cancer were analyzed in subgroups by sex, age, region, and climate classification. Estimated annual percentage change was used to describe liver cancer trends in various regions, and partial correlation was applied to explore associations between LASMR and latitude.
UNASSIGNED: In China, the average LASMR decreased from 28.79 in 2013 to 26.38 per 100,000 in 2020 among men and 11.09 to 9.83 per 100,000 among women. This decline in mortality was consistent across all age groups. Geographically, Guangxi had the highest LASMR for men in China, with a rate of 50.15 per 100,000, while for women, it was Heilongjiang, with a rate of 16.64 per 100,000. Within these regions, the LASMR among men in most parts of Guangxi ranged from 32.32 to 74.98 per 100,000, whereas the LASMR among women in the majority of Heilongjiang ranged from 13.72 to 21.86 per 100,000. The trend of LASMR varied among regions. For both men and women, Guizhou showed an increasing trend in LASMR from 2013 to 2020, with estimated annual percentage changes ranging from 10.05% to 29.07% and from 10.09% to 21.71%, respectively. Both men and women observed an increase in LASMR with increasing latitude below the 40th parallel. However, overall, LASMR in men was positively correlated with latitude (R=0.225; P<.001), while in women, it showed a negative correlation (R=0.083; P=.04). High LASMR areas among men aligned with subtropical zones, like Cwa and Cfa. The age group 65 years and older, the southern region, and the Cwa climate zone had the highest YLL rates at 4850.50, 495.50, and 440.17 per 100,000, respectively. However, the overall trends in these groups showed a decline over the period.
UNASSIGNED: Despite the declining overall trend of liver cancer in China, there are still marked disparities between regions and populations. Future prevention and control should focus on high-risk regions and populations to further reduce the burden of liver cancer in China.
■这项研究的目的是通过探索不同地理区域内肝癌死亡率的时空趋势和由其导致的寿命损失(YLL)来确定肝癌的地理差异。气候区,和中国的人口群体。
■使用2013年至2020年国家死亡监测系统的数据来计算中国肝癌的年龄标准化死亡率(LASMR)和YLL。按性别分组分析肝癌的空间分布和时间变化趋势,年龄,区域,和气候分类。估计的年度百分比变化被用来描述不同地区的肝癌趋势,并应用偏相关来探讨LASMR与纬度之间的关联。
■在中国,男性LASMR平均值从2013年的28.79降至2020年的26.38/100,000,女性为11.09降至9.83/100,000.死亡率的下降在所有年龄组都是一致的。地理上,广西是中国男性LASMR最高的国家,比率为50.15/10万,而对于女性来说,那是黑龙江,比率为16.64/100,000。在这些地区,广西大部分地区男性的LASMR为32.32至74.98/100,000,而大部分黑龙江地区女性的LASMR为13.72至21.86/100,000。LASMR的趋势因地区而异。对男人和女人来说,从2013年到2020年,贵州LASMR呈增长趋势,估计年度百分比变化范围从10.05%到29.07%,从10.09%到21.71%,分别。男性和女性都观察到LASMR的增加,纬度在40平行以下增加。然而,总的来说,男性LASMR与纬度呈正相关(R=0.225;P<.001),而在女性中,呈负相关(R=0.083;P=.04)。男性中的高LASMR地区与亚热带地区一致,比如Cwa和Cfa.65岁及以上年龄组,南部地区,和Cwa气候区的YLL率最高,分别为每100,000年4850.50、495.50和440.17。然而,这些群体的总体趋势在此期间有所下降。
■尽管中国肝癌总体呈下降趋势,地区和人口之间仍然存在明显的差异。未来防治工作应重点关注高危地区和人群,以进一步降低我国肝癌的负担。