PDF(Pubmed)
Abstract：
OBJECTIVE: Healthy diets and diets rich in phytochemicals can have health-promoting benefits in prostate cancer. Therefore, this study aimed to explore the possible association between Healthy Diet Indicator (HDI) and Phytochemical Index (PI) with prostate cancer odds ratio.
METHODS: This is a case-control study conducted in Shiraz, Iran, involving 62 newly diagnosed prostate cancer cases and 63 hospital-based controls. The study collected demographic and anthropometric data, as well as dietary intake information via a semi-quantitative food frequency questionnaire. Logistic regression models were employed to evaluate the association between HDI and PI with prostate cancer.
RESULTS: The study included 120 participants and found that individuals with higher HDI and PI scores had a lower odds ratio of prostate cancer (HDI: odds ratio (OR): 0.322 - confidence interval (CI) 95%: 0.14-0.700 - PI: OR: 0.426 - CI 95%: 0.204-0.888). After adjusting for potential confounders, a lower odds ratio of prostate cancer was observed specifically among those with higher HDI scores (OR: 0.376 - CI 95%: 0.163-0.868).
CONCLUSIONS: The findings of the present study suggest that adopting healthier dietary habits rich in dietary phytochemicals could be effective in preventing and halting the progression of prostate cancer.
METHODS: This is a case-control study conducted in Shiraz, Iran, involving 62 newly diagnosed prostate cancer cases and 63 hospital-based controls. The study collected demographic and anthropometric data, as well as dietary intake information via a semi-quantitative food frequency questionnaire. Logistic regression models were employed to evaluate the association between HDI and PI with prostate cancer.
RESULTS: The study included 120 participants and found that individuals with higher HDI and PI scores had a lower odds ratio of prostate cancer (HDI: odds ratio (OR): 0.322 - confidence interval (CI) 95%: 0.14-0.700 - PI: OR: 0.426 - CI 95%: 0.204-0.888). After adjusting for potential confounders, a lower odds ratio of prostate cancer was observed specifically among those with higher HDI scores (OR: 0.376 - CI 95%: 0.163-0.868).
CONCLUSIONS: The findings of the present study suggest that adopting healthier dietary habits rich in dietary phytochemicals could be effective in preventing and halting the progression of prostate cancer.
摘要：
目的：健康饮食和富含植物化学物质的饮食可以在前列腺癌中促进健康。因此,本研究旨在探讨健康饮食指标（HDI）和植物化学指数（PI）与前列腺癌比值比之间的可能关联。
方法：这是一项在设拉子进行的病例对照研究，伊朗,涉及62例新诊断的前列腺癌病例和63例医院控制。这项研究收集了人口统计和人体测量数据，以及通过半定量食物频率问卷获得的饮食摄入量信息。采用Logistic回归模型评估HDI和PI与前列腺癌的相关性。
结果：该研究包括120名参与者，发现HDI和PI评分较高的个体患前列腺癌的比值比较低（HDI：比值比（OR）：0.322-置信区间（CI）95％：0.14-0.700-PI：OR：0.426-CI95％：0.204-0.888）。在调整了潜在的混杂因素后，尤其是在HDI评分较高的人群中,前列腺癌的比值比较低(OR:0.376-CI95%:0.163~0.868).
结论：本研究的结果表明，采用富含膳食植物化学物质的更健康的饮食习惯可以有效预防和阻止前列腺癌的进展。
方法：这是一项在设拉子进行的病例对照研究，伊朗,涉及62例新诊断的前列腺癌病例和63例医院控制。这项研究收集了人口统计和人体测量数据，以及通过半定量食物频率问卷获得的饮食摄入量信息。采用Logistic回归模型评估HDI和PI与前列腺癌的相关性。
结果：该研究包括120名参与者，发现HDI和PI评分较高的个体患前列腺癌的比值比较低（HDI：比值比（OR）：0.322-置信区间（CI）95％：0.14-0.700-PI：OR：0.426-CI95％：0.204-0.888）。在调整了潜在的混杂因素后，尤其是在HDI评分较高的人群中,前列腺癌的比值比较低(OR:0.376-CI95%:0.163~0.868).
结论：本研究的结果表明，采用富含膳食植物化学物质的更健康的饮食习惯可以有效预防和阻止前列腺癌的进展。
