METHODS: This prospective observational cohort study of spinal sarcopenia (SarcoSpine) was conducted at a single center. One hundred and ten consecutive individuals who completed the baseline survey, including conventional sarcopenic indices, lumbar spine three-dimensional magnetic resonance imaging, isokinetic lumbar extensor strength, and physical performance tests (Short Physical Performance Battery, Berg Balance Scale, and Back Performance Scale [BPS]), were enrolled. A multivariate linear regression analysis was performed to determine the variables for evaluating their association with LEM strength.
RESULTS: Among the conventional sarcopenic indices, gait speed was significantly correlated with Short Physical Performance Battery results and Berg Balance Scale score in men and women. Handgrip strength was significantly correlated with the BPS score for both sexes. In the multivariable linear regression, age (β = -2.12, p < .01) and BPS score (β = -3.54, p = .01, R2 = .29) were independent indicators of LEM strength.
CONCLUSIONS: Our findings reveal the substantial association between LEM strength and BPS score in older women. The targeted intervention aimed at improving the LEMs strength would be needed to enhance physical performance in the aging population.
方法:这项脊髓少肌症(SarcoSpine)的前瞻性观察性队列研究是在一个中心进行的。连续一百一十个人完成基线调查,包括常规的节肉指数,腰椎三维磁共振成像,等速腰椎伸肌强度,和物理性能测试(短物理性能电池,Berg平衡量表,和BackPerformanceScale[BPS]),已注册。进行多元线性回归分析以确定用于评估其与LEM强度的关联的变量。
结果:在常规的节肉指数中,在男性和女性中,步态速度与短体能电池结果和Berg平衡量表得分显着相关。两性的握力与BPS评分显着相关。在多元线性回归中,年龄(β=-2.12,p<.01)和BPS评分(β=-3.54,p=.01,R2=.29)是LEM强度的独立指标。
结论:我们的发现揭示了老年女性LEM强度与BPS评分之间的实质性关联。需要旨在提高LEM强度的有针对性的干预措施,以提高人口老龄化的身体表现。