Abstract：
Candidiasis is a common fungal infection, with Candida tropicalis infections being relatively rare. These infections develop into skin fungal infections under conditions such as broad-spectrum antibiotic use, diabetes, and immunosuppression. Traditionally, antifungal drugs have been the primary treatment; however, issues like hepatotoxicity and the need for long-term use persist. Consequently, new treatment approaches are essential. Most previous reports have focused on Candida albicans, with fewer addressing Candida tropicalis. This study reports a case where a patient with a skin Candida tropicalis infection was treated with a combination of surgery and ALA photodynamic therapy(635 nm, 120 J/cm2, 177 mW/cm2). After just one session of this combined treatment, the patient achieved significant clinical remission. Therefore, the combination of surgery and ALA-PDT may offer a safe and effective treatment option.
摘要：
念珠菌病是一种常见的真菌感染，热带念珠菌感染相对罕见。这些感染在广谱抗生素使用等条件下发展为皮肤真菌感染，糖尿病,和免疫抑制。传统上,抗真菌药物一直是主要的治疗方法;然而,肝毒性和长期使用的需要等问题仍然存在。因此,新的治疗方法至关重要。以前的报道大多集中在白色念珠菌上,较少寻址热带念珠菌。本研究报告了一例皮肤热带念珠菌感染的患者采用手术和ALA光动力疗法（635nm，120J/cm2，177mW/cm2）。经过一次联合治疗，患者获得了显著的临床缓解。因此,手术和ALA-PDT的联合治疗可能提供安全有效的治疗选择.
