%0 Journal Article
%T Successful combined treatment with surgery and ALA-PDT for cutaneous infection by candida tropicalis: A case report and literature review.
%A He X
%A Lu Y
%J Photodiagnosis Photodyn Ther
%V 49
%N 0
%D 2024 Aug 6
%M 39117160
%F 3.577
%R 10.1016/j.pdpdt.2024.104303
%X Candidiasis is a common fungal infection, with Candida tropicalis infections being relatively rare. These infections develop into skin fungal infections under conditions such as broad-spectrum antibiotic use, diabetes, and immunosuppression. Traditionally, antifungal drugs have been the primary treatment; however, issues like hepatotoxicity and the need for long-term use persist. Consequently, new treatment approaches are essential. Most previous reports have focused on Candida albicans, with fewer addressing Candida tropicalis. This study reports a case where a patient with a skin Candida tropicalis infection was treated with a combination of surgery and ALA photodynamic therapy(635 nm, 120 J/cm2, 177 mW/cm2). After just one session of this combined treatment, the patient achieved significant clinical remission. Therefore, the combination of surgery and ALA-PDT may offer a safe and effective treatment option.