METHODS: A retrospective analysis of medical records from patients who visited a tinnitus clinic at a tertiary university hospital between March 2020 and December 2023 was conducted. Inclusion criteria were non-pulsatile subjective tinnitus lasting over three months, and ECochG performed at initial evaluation. Audiological assessments and ECochG results were analyzed, with the SP/AP ratio being a focal point.
RESULTS: Among 256 patients, an elevated SP/AP ratio was observed in 37.5 % of patients. No significant difference in ECochG outcomes was noted based on tinnitus laterality. Patients with an elevated SP/AP ratio reported more sleep disturbances, higher depression scores, attention problems, and aural fullness. These patients also exhibited lower loudness discomfort levels and low-frequency hearing losses. Significant correlations were found between elevated SP/AP ratios and DPOAE responses.
CONCLUSIONS: The findings highlight the SP/AP ratio in ECochG as a valuable biomarker for assessing clinical and psychological aspects of tinnitus, indicating its potential utility in tailoring treatment strategies. Elevated SP/AP ratios were associated with sleep disturbances, depression, attention problems, aural fullness, hyperacusis, and low-frequency hearing loss, suggesting a complex interplay between cochlear pathology and tinnitus perception. This study underscores the need for a nuanced understanding of ECochG results in the clinical evaluation of tinnitus, potentially guiding more personalized management approaches.
方法:对2020年3月至2023年12月在三级大学医院就诊耳鸣诊所的患者的病历进行了回顾性分析。纳入标准为持续三个月以上的非搏动性主观耳鸣,和ECochG在初始评估时进行。对听力学评估和ECochG结果进行了分析,SP/AP比率是一个焦点。
结果:在256名患者中,在37.5%的患者中观察到SP/AP比值升高.根据耳鸣侧向性,ECochG结果没有显着差异。SP/AP比值升高的患者报告了更多的睡眠障碍,更高的抑郁分数,注意问题,和听觉丰满。这些患者还表现出较低的响度不适水平和低频听力损失。SP/AP比值升高与DPOAE反应显著相关。
结论:研究结果强调了ECochG中的SP/AP比率是评估耳鸣的临床和心理方面的有价值的生物标志物,表明其在定制治疗策略方面的潜在效用。SP/AP比率升高与睡眠障碍有关,抑郁症,注意问题,听觉丰满,高音,和低频听力损失,这表明耳蜗病理学和耳鸣感知之间存在复杂的相互作用。这项研究强调了在耳鸣的临床评估中需要对ECochG结果进行细致的理解,可能指导更个性化的管理方法。