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Abstract：
BACKGROUND: There is no replacement for blood, and patients requiring transfusion depend on human donors, most of whom are family donors. Family donors may deny engagement in high-risk activities, which threaten the safety of donated blood. This study determined frequency of self-reported high-risk behaviors among replacement donors.
METHODS: This retrospective study recruited 1317 donor records from 2017-2020, at Mankranso Hospital, Ghana. Data from archived donor questionnaires were extracted and analyzed with SPSS and GraphPad. Frequencies, associations, and quartiles were presented.
RESULTS: The donors were predominantly males (84.4%), 17-26 years old (43.7%), informal workers (71.8%), rural inhabitants (56.5%), first-time (65.0%), and screened in the rainy season (56.3%). Donation frequency was significantly associated with age, sex, occupation, and residence. Repeat donors were significantly older (p≤0.001). More males than females were deferred (p = 0.008), drug addicts (p = 0.001), had body modifications (p = 0.025), multiple sexual partners (p = 0.045), and STIs (p≤0.001), whereas, more females were recently treated (p = 0.044). Weight loss (p = 0.005) and pregnancy (p = 0.026) were frequent among 17-26-year group, whereas, tuberculosis was frequent among 37-60-year group (p = 0.009). More first-time donors were unwell (p = 0.005), deferred (p≤0.001), pregnant (p = 0.002), drug addicts, had impending rigorous activity (p = 0.037), body modifications (p = 0.001), multiple sexual partners (p = 0.030), and STIs (p = 0.008). STIs were frequent in the dry season (p = 0.010). First-time donors had reduced hemoglobin (p = 0.0032), weight (p = 0.0003), and diastolic pressure (p = 0.0241).
CONCLUSIONS: Donation frequency was associated with age, sex, occupation, and residence, with first-time donors younger than repeat donors. Deferral from donation, drug addiction, body modification, multiple sexual partners, and STIs were frequent among males, whereas, more females received treatment. Tuberculosis was frequently reported among older adults, whereas, weight loss and pregnancy were frequent among younger individuals. More first-time donors reported being unwell, deferred, drug addiction, body modifications, multiple sexual partners, STIs, and pregnant. Hemoglobin, weight, and diastolic BP were reduced among first-time donors.
METHODS: This retrospective study recruited 1317 donor records from 2017-2020, at Mankranso Hospital, Ghana. Data from archived donor questionnaires were extracted and analyzed with SPSS and GraphPad. Frequencies, associations, and quartiles were presented.
RESULTS: The donors were predominantly males (84.4%), 17-26 years old (43.7%), informal workers (71.8%), rural inhabitants (56.5%), first-time (65.0%), and screened in the rainy season (56.3%). Donation frequency was significantly associated with age, sex, occupation, and residence. Repeat donors were significantly older (p≤0.001). More males than females were deferred (p = 0.008), drug addicts (p = 0.001), had body modifications (p = 0.025), multiple sexual partners (p = 0.045), and STIs (p≤0.001), whereas, more females were recently treated (p = 0.044). Weight loss (p = 0.005) and pregnancy (p = 0.026) were frequent among 17-26-year group, whereas, tuberculosis was frequent among 37-60-year group (p = 0.009). More first-time donors were unwell (p = 0.005), deferred (p≤0.001), pregnant (p = 0.002), drug addicts, had impending rigorous activity (p = 0.037), body modifications (p = 0.001), multiple sexual partners (p = 0.030), and STIs (p = 0.008). STIs were frequent in the dry season (p = 0.010). First-time donors had reduced hemoglobin (p = 0.0032), weight (p = 0.0003), and diastolic pressure (p = 0.0241).
CONCLUSIONS: Donation frequency was associated with age, sex, occupation, and residence, with first-time donors younger than repeat donors. Deferral from donation, drug addiction, body modification, multiple sexual partners, and STIs were frequent among males, whereas, more females received treatment. Tuberculosis was frequently reported among older adults, whereas, weight loss and pregnancy were frequent among younger individuals. More first-time donors reported being unwell, deferred, drug addiction, body modifications, multiple sexual partners, STIs, and pregnant. Hemoglobin, weight, and diastolic BP were reduced among first-time donors.
摘要：
背景：没有替代血液，需要输血的患者依赖于人类捐赠者，其中大多数是家庭捐赠者。家庭捐赠者可能拒绝参与高风险活动，威胁到捐献血液的安全.这项研究确定了替代供体中自我报告的高风险行为的频率。
方法：这项回顾性研究从2017-2020年在Mankranso医院收集了1317份捐赠者记录，加纳。从存档的供体问卷中提取数据，并使用SPSS和GraphPad进行分析。频率,协会,并展示了四分位数。
结果：捐献者主要是男性（84.4%），17-26岁（43.7%），非正规工人(71.8%)，农村居民(56.5%)，首次(65.0%)，并在雨季筛选(56.3%)。捐赠频率与年龄显著相关，性别,职业,和居住。重复供者明显年龄较大（p≤0.001）。推迟的男性多于女性（p=0.008），吸毒者（p=0.001），有身体修饰(p=0.025)，多个性伴侣（p=0.045），和性传播感染(p≤0.001)，然而,最近接受治疗的女性更多（p=0.044）。体重下降（p=0.005）和怀孕（p=0.026）在17-26岁组频繁，然而,结核病在37~60岁组较为常见(p=0.009).更多的首次捐献者身体不适（p=0.005），递延(p≤0.001)，怀孕（p=0.002），吸毒者,具有即将到来的严格活动(p=0.037)，身体修饰(p=0.001)，多个性伴侣（p=0.030），和性传播感染(p=0.008)。性传播感染在旱季频繁发生(p=0.010)。首次捐献者的血红蛋白减少（p=0.0032），重量（p=0.0003），和舒张压（p=0.0241）。
结论：捐赠频率与年龄有关，性别,职业,和居住,首次捐献者比重复捐献者年轻。推迟捐赠，毒瘾,车身改造，多个性伴侣,性传播感染在男性中很常见，然而,更多女性接受治疗。结核病经常在老年人中报告，然而,体重减轻和怀孕在年轻个体中很常见.更多的首次捐助者报告身体不适，延期，毒瘾,身体修改，多个性伴侣,性传播感染,怀孕了.血红蛋白,体重,首次供者的舒张压降低。
方法：这项回顾性研究从2017-2020年在Mankranso医院收集了1317份捐赠者记录，加纳。从存档的供体问卷中提取数据，并使用SPSS和GraphPad进行分析。频率,协会,并展示了四分位数。
结果：捐献者主要是男性（84.4%），17-26岁（43.7%），非正规工人(71.8%)，农村居民(56.5%)，首次(65.0%)，并在雨季筛选(56.3%)。捐赠频率与年龄显著相关，性别,职业,和居住。重复供者明显年龄较大（p≤0.001）。推迟的男性多于女性（p=0.008），吸毒者（p=0.001），有身体修饰(p=0.025)，多个性伴侣（p=0.045），和性传播感染(p≤0.001)，然而,最近接受治疗的女性更多（p=0.044）。体重下降（p=0.005）和怀孕（p=0.026）在17-26岁组频繁，然而,结核病在37~60岁组较为常见(p=0.009).更多的首次捐献者身体不适（p=0.005），递延(p≤0.001)，怀孕（p=0.002），吸毒者,具有即将到来的严格活动(p=0.037)，身体修饰(p=0.001)，多个性伴侣（p=0.030），和性传播感染(p=0.008)。性传播感染在旱季频繁发生(p=0.010)。首次捐献者的血红蛋白减少（p=0.0032），重量（p=0.0003），和舒张压（p=0.0241）。
结论：捐赠频率与年龄有关，性别,职业,和居住,首次捐献者比重复捐献者年轻。推迟捐赠，毒瘾,车身改造，多个性伴侣,性传播感染在男性中很常见，然而,更多女性接受治疗。结核病经常在老年人中报告，然而,体重减轻和怀孕在年轻个体中很常见.更多的首次捐助者报告身体不适，延期，毒瘾,身体修改，多个性伴侣,性传播感染,怀孕了.血红蛋白,体重,首次供者的舒张压降低。
