Abstract：
Metabolic dysfunction-associated fatty liver disease (MAFLD) and viral hepatitis due to chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infection are common liver diseases worldwide. Excessive alcohol consumption and alcoholic liver disease (ALD) are also emerging health problems. Therefore, in clinical practice, we may encounter subjects with dual etiology of liver diseases such as coexisting MAFLD/HBV, MAFLD/HCV, and MAFLD/ALD. In this review, we summarize the epidemiology, clinical features, and mutual interactions of MAFLD with coexisting HBV, HCV, or ALD. The impact of MAFLD on the progression of liver diseases and treatment outcomes in patients with chronic viral hepatitis and the clinical questions to be addressed regarding dual MAFLD and ALD are also discussed.
摘要：
由慢性乙型肝炎病毒（HBV）或丙型肝炎病毒（HCV）感染引起的代谢功能障碍相关脂肪性肝病（MAFLD）和病毒性肝炎是全球常见的肝病。过度饮酒和酒精性肝病（ALD）也是新出现的健康问题。因此,在临床实践中，我们可能会遇到与肝脏疾病的双重病因，如共存MAFLD/HBV，MAFLD/HCV,和MAFLD/ALD。在这次审查中,我们总结了流行病学，临床特征,MAFLD与共存HBV的相互作用，HCV,或者ALD.还讨论了MAFLD对慢性病毒性肝炎患者肝病进展和治疗结果的影响，以及关于双MAFLD和ALD的临床问题。
