Abstract：
Current guidelines recommend screening with serum M-protein and serum-free light chain analysis (S-FLC) when an M-protein-related disorder is suspected. Many patients with multiple myeloma will be overlooked if only serum M-protein is measured. Despite this, the general practitioners in some areas of Denmark cannot order S-FLC. This review aims to disseminate knowledge of the S-FLC analysis, its applicability, and limitations in the diagnostic workup for suspected monoclonal gammopathies.
摘要：
当怀疑M蛋白相关疾病时，当前指南建议使用血清M蛋白和无血清轻链分析（S-FLC）进行筛查。如果仅测量血清M蛋白，许多多发性骨髓瘤患者将被忽视。尽管如此,丹麦某些地区的全科医生不能订购S-FLC。这篇综述旨在传播S-FLC分析的知识，其适用性，以及可疑单克隆丙种球蛋白的诊断检查的局限性。
