{Reference Type}: Journal Article {Title}: Serum-free light chains in the evaluation of M-component disease. {Author}: Rasch S;Hansen CT;Abilgaard N; {Journal}: Ugeskr Laeger {Volume}: 186 {Issue}: 29 {Year}: 2024 Jul 15 暂无{DOI}: 10.61409/V12230766 {Abstract}: Current guidelines recommend screening with serum M-protein and serum-free light chain analysis (S-FLC) when an M-protein-related disorder is suspected. Many patients with multiple myeloma will be overlooked if only serum M-protein is measured. Despite this, the general practitioners in some areas of Denmark cannot order S-FLC. This review aims to disseminate knowledge of the S-FLC analysis, its applicability, and limitations in the diagnostic workup for suspected monoclonal gammopathies.