PDF(Pubmed)
Abstract：
UNASSIGNED: The Montreal Cognitive Assessment (MoCA) is recommended by the Movement Disorder Society for cognitive testing in movement disorders including Parkinson\'s disease (PD) and lewy body dementia. Few studies have compared cognitive screening instruments in these diseases, which overlap clinically.
UNASSIGNED: To compare the MoCA and Quick Mild Cognitive Impairment (Qmci) screen in this population.
UNASSIGNED: Patients attending memory and movement disorder clinics associated with a university hospital had the MoCA and Qmci screen performed and diagnostic accuracy compared with the area under the receiver operating characteristic curve (AUC). Duration and severity of movement disorders was assessed using the Unified PD Rating Scale (UPDRS).
UNASSIGNED: In total, 133 assessments were available, median age 74±5. Median education was 11±4 years and 65% were male. Median total UPDRS score was 37±26. Median Qmci screen was 51±27, median MoCA was 19±10. There were statistically significant differences in test scores between those with subjective symptoms but normal cognition, mild cognitive impairment (MCI) and dementia (p < 0.001). The Qmci screen had significantly greater accuracy differentiating normal cognition from MCI versus the MoCA (AUC 0.90 versus 0.72, p = 0.01). Both instruments had similar accuracy in identifying cognitive impairment and separating MCI from dementia. The median administration time for the Qmci screen and MoCA were 5.19 and 9.24 minutes (p < 0.001), respectively.
UNASSIGNED: Both the MoCA and Qmci screen have good to excellent accuracy in a population with movement disorders experiencing cognitive symptoms. The Qmci screen was significantly more accurate for those with early symptoms and had a shorter administration time.
UNASSIGNED: To compare the MoCA and Quick Mild Cognitive Impairment (Qmci) screen in this population.
UNASSIGNED: Patients attending memory and movement disorder clinics associated with a university hospital had the MoCA and Qmci screen performed and diagnostic accuracy compared with the area under the receiver operating characteristic curve (AUC). Duration and severity of movement disorders was assessed using the Unified PD Rating Scale (UPDRS).
UNASSIGNED: In total, 133 assessments were available, median age 74±5. Median education was 11±4 years and 65% were male. Median total UPDRS score was 37±26. Median Qmci screen was 51±27, median MoCA was 19±10. There were statistically significant differences in test scores between those with subjective symptoms but normal cognition, mild cognitive impairment (MCI) and dementia (p < 0.001). The Qmci screen had significantly greater accuracy differentiating normal cognition from MCI versus the MoCA (AUC 0.90 versus 0.72, p = 0.01). Both instruments had similar accuracy in identifying cognitive impairment and separating MCI from dementia. The median administration time for the Qmci screen and MoCA were 5.19 and 9.24 minutes (p < 0.001), respectively.
UNASSIGNED: Both the MoCA and Qmci screen have good to excellent accuracy in a population with movement disorders experiencing cognitive symptoms. The Qmci screen was significantly more accurate for those with early symptoms and had a shorter administration time.
摘要：
■蒙特利尔认知评估（MoCA）是运动障碍协会推荐的认知测试，包括帕金森氏病（PD）和路易体痴呆。很少有研究比较这些疾病的认知筛查工具，在临床上重叠。
■比较该人群的MoCA和快速轻度认知障碍（Qmci）屏幕。
■参加与大学医院相关的记忆和运动障碍诊所的患者进行了MoCA和Qmci筛查，并将诊断准确性与受试者工作特征曲线（AUC）下的面积进行了比较。使用统一PD评定量表（UPDRS）评估运动障碍的持续时间和严重程度。
■总共，有133项评估，中位年龄74±5。教育中位数为11±4年，男性占65％。UPDRS总分中位数为37±26。Qmci筛选中位数为51±27，MoCA中位数为19±10。有主观症状但认知正常者的测试成绩有统计学上的显著差异,轻度认知障碍（MCI）和痴呆（p<0.001）。与MoCA相比，Qmci筛查将正常认知与MCI区分开的准确性明显更高（AUC0.90对0.72，p=0.01）。两种仪器在识别认知障碍和将MCI与痴呆分开方面具有相似的准确性。Qmci筛查和MoCA的中位给药时间分别为5.19和9.24分钟（p<0.001），分别。
■MoCA和Qmci屏幕在出现认知症状的运动障碍人群中都具有良好的准确性。对于有早期症状的患者，Qmci筛查明显更准确，给药时间更短。
■比较该人群的MoCA和快速轻度认知障碍（Qmci）屏幕。
■参加与大学医院相关的记忆和运动障碍诊所的患者进行了MoCA和Qmci筛查，并将诊断准确性与受试者工作特征曲线（AUC）下的面积进行了比较。使用统一PD评定量表（UPDRS）评估运动障碍的持续时间和严重程度。
■总共，有133项评估，中位年龄74±5。教育中位数为11±4年，男性占65％。UPDRS总分中位数为37±26。Qmci筛选中位数为51±27，MoCA中位数为19±10。有主观症状但认知正常者的测试成绩有统计学上的显著差异,轻度认知障碍（MCI）和痴呆（p<0.001）。与MoCA相比，Qmci筛查将正常认知与MCI区分开的准确性明显更高（AUC0.90对0.72，p=0.01）。两种仪器在识别认知障碍和将MCI与痴呆分开方面具有相似的准确性。Qmci筛查和MoCA的中位给药时间分别为5.19和9.24分钟（p<0.001），分别。
■MoCA和Qmci屏幕在出现认知症状的运动障碍人群中都具有良好的准确性。对于有早期症状的患者，Qmci筛查明显更准确，给药时间更短。
