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Abstract：
OBJECTIVE: To determine the genetic effects of panoramic radiography on the epithelial cells of the buccal mucosa by examining the micronucleus formation in these cells.
METHODS: In this cross-sectional study, exfoliative cytology samples were prepared from the buccal mucosa of 36 patients immediately before and 10 days after panoramic radiography. The samples were prepared using liquid-based cytology with Papanicolaou staining. The slides were simultaneously evaluated by two expert pathologists and the ratio of the number of cells with micronuclei to the total number of cells on the slide was reported as a percentage. Data analysis was done using paired-samples T test, Pearson\'s correlation coefficient, and covariance analysis (α = 0.05).
RESULTS: The study sample consisted of 24 (66.67%) males and 12 females (33.33%) with a mean (SD) age of 27.36 (8.19) years. The frequency of cells with micronucleus before and after panoramic radiography was not statistically different (p = 0.468). Additionally, the frequency of micronucleated cells was not correlated with age (p = 0.737) and sex (p = 0.211).
CONCLUSIONS: Panoramic exposure slightly increased the frequency of cells with micronucleus in epithelial cells of the buccal mucosa. However, this increase was not statistically significant.
METHODS: In this cross-sectional study, exfoliative cytology samples were prepared from the buccal mucosa of 36 patients immediately before and 10 days after panoramic radiography. The samples were prepared using liquid-based cytology with Papanicolaou staining. The slides were simultaneously evaluated by two expert pathologists and the ratio of the number of cells with micronuclei to the total number of cells on the slide was reported as a percentage. Data analysis was done using paired-samples T test, Pearson\'s correlation coefficient, and covariance analysis (α = 0.05).
RESULTS: The study sample consisted of 24 (66.67%) males and 12 females (33.33%) with a mean (SD) age of 27.36 (8.19) years. The frequency of cells with micronucleus before and after panoramic radiography was not statistically different (p = 0.468). Additionally, the frequency of micronucleated cells was not correlated with age (p = 0.737) and sex (p = 0.211).
CONCLUSIONS: Panoramic exposure slightly increased the frequency of cells with micronucleus in epithelial cells of the buccal mucosa. However, this increase was not statistically significant.
摘要：
目的：通过检查口腔黏膜上皮细胞中的微核形成来确定全景射线照相术对这些细胞的遗传影响。
方法：在这项横断面研究中，在全景X线摄影之前和之后10天，从36例患者的颊粘膜中制备了脱落细胞学样本。使用基于液体的细胞学和Papanicolaou染色制备样品。由两名专家病理学家同时评估载玻片,并以百分比报告具有微核的细胞数量与载玻片上细胞总数的比率。数据分析采用配对样本T检验，皮尔逊相关系数，和协方差分析(α=0.05)。
结果：研究样本包括24名男性（66.67%）和12名女性（33.33%），平均（SD）年龄为27.36（8.19）岁。全景X线摄影前后微核细胞的频率无统计学差异（p=0.468）。此外,微核细胞的频率与年龄（p=0.737）和性别（p=0.211）无关。
结论：全景暴露会稍微增加颊粘膜上皮细胞中微核细胞的频率。然而,这一增加没有统计学意义.
方法：在这项横断面研究中，在全景X线摄影之前和之后10天，从36例患者的颊粘膜中制备了脱落细胞学样本。使用基于液体的细胞学和Papanicolaou染色制备样品。由两名专家病理学家同时评估载玻片,并以百分比报告具有微核的细胞数量与载玻片上细胞总数的比率。数据分析采用配对样本T检验，皮尔逊相关系数，和协方差分析(α=0.05)。
结果：研究样本包括24名男性（66.67%）和12名女性（33.33%），平均（SD）年龄为27.36（8.19）岁。全景X线摄影前后微核细胞的频率无统计学差异（p=0.468）。此外,微核细胞的频率与年龄（p=0.737）和性别（p=0.211）无关。
结论：全景暴露会稍微增加颊粘膜上皮细胞中微核细胞的频率。然而,这一增加没有统计学意义.
