Abstract：
Men with germline pathogenic variants in BRCA1 or BRCA2 genes are at an increased lifetime risk for developing breast cancer, prostate cancer, and pancreatic cancer. Men report that managing clinical care is challenging because they are under-informed about their cancer risks. As the demand for genetic testing has increased, so too has the need to relay accurate and relatable genetic health information. This research developed and assessed the acceptability and appropriateness of a psychoeducational graphic novel designed for men to improve their cancer risk knowledge, manage their cancer-related uncertainty, and increase their intent to disclose their BRCA1/2 risks to family members and healthcare providers. Through purposive and snowball sampling, men (n = 20) and certified genetic counselors (CGCs; n = 15) participated in semi-structured interviews assessing the acceptability and appropriateness of the graphic novel. Interviews were audio-recorded, transcribed, and thematically analyzed. Both reported that the graphic novel confirmed risk information provided helpful resources, included relatable storylines, and had a unique visual appeal. Some men remained unsure about how to perform recommended screenings and how to talk to family members, particularly children, about BRCA1/2 test results after assessing the graphic novel. CGCs also discussed the helpfulness of the graphic novel for their practice. Given that this psychoeducational graphic novel was appealing to men and CGCs, it shows promise as an acceptable approach that may assist men in managing their cancer risks and communicating their genetic risk information to family members and healthcare providers.
摘要：
BRCA1或BRCA2基因中具有种系致病变异的男性患乳腺癌的终生风险增加，前列腺癌,还有胰腺癌.男性报告说，管理临床护理是具有挑战性的，因为他们对自己的癌症风险知之甚少。随着基因检测需求的增加，因此，也需要传递准确和相关的遗传健康信息。这项研究开发并评估了为男性设计的心理教育图像小说的可接受性和适当性，以提高他们的癌症风险知识，管理他们与癌症相关的不确定性，并增加他们向家庭成员和医疗保健提供者披露BRCA1/2风险的意图。通过目的性和雪球采样，男性(n=20)和经过认证的遗传咨询师(CGCs;n=15)参加了半结构化访谈,评估了图画小说的可接受性和适当性.采访是录音的，转录，并进行了主题分析。两者都报告说，图形小说确认的风险信息提供了有用的资源，包括相关的故事情节，并具有独特的视觉吸引力。一些男人仍然不确定如何进行推荐的筛查以及如何与家人交谈，特别是儿童,关于BRCA1/2测试结果后评估图形小说。CGCs还讨论了图形小说对他们实践的帮助。鉴于这部心理教育小说对男性和CGCs很有吸引力，它显示了作为一种可接受的方法的希望，可以帮助男性管理他们的癌症风险，并将他们的遗传风险信息传达给家庭成员和医疗保健提供者。
